SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ojl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0A_C_GLYC73_0
(NONSTRUCTURAL
PROTEIN 1)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		4 / 4 ASP A 274
ASP A 162
SER A 161
ARG A 188
 None
 1.43A 2z0aC-1ojlA:
undetectable		 2z0aC-1ojlA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LBD_A_9CRA424_1
(RETINOIC ACID
RECEPTOR GAMMA)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 12 ALA A 364
LEU A 361
ARG A 329
PHE A 341
ILE A 386
 None
 1.40A 3lbdA-1ojlA:
0.0		 3lbdA-1ojlA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		4 / 6 ARG A 283
GLY A 243
ASN A 197
GLU A 241
 None
 1.32A 4g0vB-1ojlA:
0.0		 4g0vB-1ojlA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		4 / 8 SER A 311
ASP A 170
GLU A 308
GLN A 314
 None
 1.09A 4lnwA-1ojlA:
0.0		 4lnwA-1ojlA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 10 LEU A 277
CYH A 198
LEU A 239
ALA A 279
LEU A 302
 None
 1.18A 4p65A-1ojlA:
undetectable
4p65B-1ojlA:
undetectable
4p65F-1ojlA:
undetectable
4p65H-1ojlA:
undetectable		 4p65A-1ojlA:
5.30
4p65B-1ojlA:
8.33
4p65F-1ojlA:
8.33
4p65H-1ojlA:
8.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 12 LEU A 302
ALA A 280
LEU A 239
ASN A 197
ALA A 179
 None
 1.26A 4x1kA-1ojlA:
undetectable
4x1kB-1ojlA:
undetectable		 4x1kA-1ojlA:
20.91
4x1kB-1ojlA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		3 / 3 LEU A 312
ARG A 313
ARG A 316
 None
 0.87A 4yiaB-1ojlA:
undetectable		 4yiaB-1ojlA:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		4 / 7 LEU A 382
LEU A 349
ALA A 323
ALA A 368
 None
 0.67A 4z90F-1ojlA:
undetectable
4z90G-1ojlA:
undetectable
4z90H-1ojlA:
undetectable
4z90J-1ojlA:
undetectable		 4z90F-1ojlA:
21.81
4z90G-1ojlA:
21.81
4z90H-1ojlA:
21.81
4z90J-1ojlA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 8 LEU A 298
PHE A 294
GLY A 243
THR A 281
LEU A 166
 None
 1.48A 5eseA-1ojlA:
undetectable		 5eseA-1ojlA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 8 ARG A 228
ALA A 232
LEU A 210
LEU A 196
LEU A 277
 None
 1.24A 5jqbA-1ojlA:
undetectable
5jqbB-1ojlA:
undetectable		 5jqbA-1ojlA:
23.38
5jqbB-1ojlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		5 / 10 PRO A 310
ALA A 179
THR A 164
ILE A 278
ALA A 280
 None
 1.37A 5vyhA-1ojlA:
0.0		 5vyhA-1ojlA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_A_ACTA403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 1ojl TRANSCRIPTIONAL
REGULATORY PROTEIN
ZRAR
(Salmonella
enterica) 		3 / 3 TYR A 300
ASP A 297
GLN A 296
 None
 0.77A 6g1pA-1ojlA:
0.0		 6g1pA-1ojlA:
22.59