SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ojz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 7 SER A 138
ARG A 150
GLN A 178
GLU A 180
 NAD  A 500 (-2.9A)
NAD  A 500 (-2.7A)
NAD  A 500 (-3.4A)
NAD  A 500 (-2.6A)
 0.88A 2c8aA-1ojzA:
26.3		 2c8aA-1ojzA:
35.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TBG_A_RTZA2_1
(CYTOCHROME P450 2D6)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		5 / 11 THR A 187
LEU A 156
VAL A  83
VAL A  76
THR A  77
 None
 1.15A 3tbgA-1ojzA:
undetectable		 3tbgA-1ojzA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 5 GLU A 133
GLY A 186
TYR A 136
ASP A  69
 NAD  A 500 (-3.2A)
None
None
None
 1.42A 3w9tD-1ojzA:
0.0		 3w9tD-1ojzA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1478_0
(MJ0495-LIKE PROTEIN)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 7 SER A  80
ASP A  79
GLY A 161
THR A 162
 None
 0.98A 4ac9C-1ojzA:
undetectable		 4ac9C-1ojzA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 7 TYR A  91
LEU A 122
TYR A 131
VAL A 194
 None
 1.35A 6g2pA-1ojzA:
undetectable		 6g2pA-1ojzA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ojz ADP-RIBOSYLTRANSFERA
SE
(Staphylococcus
aureus) 		4 / 6 ILE A  95
LEU A  92
TYR A 189
THR A 206
 None
 1.11A 6nmfN-1ojzA:
undetectable
6nmfW-1ojzA:
undetectable		 6nmfN-1ojzA:
18.12
6nmfW-1ojzA:
14.15