SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oki'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		4 / 7 VAL A  95
ILE A 114
THR A 191
GLY A  98
 None
 1.00A 3gssB-1okiA:
undetectable		 3gssB-1okiA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		5 / 8 LEU A 115
VAL A  90
LEU A 135
VAL A  62
LEU A  60
 None
 1.41A 3kp6A-1okiA:
undetectable
3kp6B-1okiA:
undetectable		 3kp6A-1okiA:
20.85
3kp6B-1okiA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		3 / 3 ILE A 114
VAL A 193
ARG A 229
 None
 0.75A 3p73A-1okiA:
0.8		 3p73A-1okiA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQ4_A_SAMA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H2)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		5 / 12 GLY A  56
SER A  96
PHE A 138
CYH A  79
GLU A  78
 None
 1.37A 3rq4A-1okiA:
undetectable		 3rq4A-1okiA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		3 / 3 TYR A 197
ARG A 131
SER A 129
 None
 1.18A 4dr2I-1okiA:
undetectable
4dr2J-1okiA:
undetectable		 4dr2I-1okiA:
22.64
4dr2J-1okiA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		4 / 6 SER A 227
LEU A 228
TYR A 176
LEU A 173
 None
 0.88A 4wozA-1okiA:
undetectable
4wozB-1okiA:
undetectable		 4wozA-1okiA:
20.59
4wozB-1okiA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		5 / 12 GLY A  56
SER A  96
PHE A 138
CYH A  79
GLU A  78
 None
 1.42A 5cprB-1okiA:
undetectable		 5cprB-1okiA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JM4_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		4 / 4 PHE A  63
ILE A  94
GLN A  69
ARG A  72
 None
 1.01A 5jm4B-1okiA:
undetectable		 5jm4B-1okiA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNA_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		3 / 3 ARG A 139
LYS A 142
TYR A  58
 None
 1.38A 6gnaA-1okiA:
undetectable		 6gnaA-1okiA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNB_A_ACTA307_0
(THIOREDOXIN
REDUCTASE)		 1oki BETA CRYSTALLIN B1
(Homo
sapiens) 		3 / 3 ARG A 139
LYS A 142
TYR A  58
 None
 1.38A 6gnbA-1okiA:
undetectable		 6gnbA-1okiA:
21.77