SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1om9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		3 / 3 GLN A 520
TYR A 610
ARG A 609
 None
 0.79A 1gtbA-1om9A:
undetectable		 1gtbA-1om9A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 10 PHE A 527
LEU A 598
VAL A 606
PHE A 630
VAL A 543
 None
 1.42A 1q23K-1om9A:
0.0		 1q23K-1om9A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 11 PRO A 503
SER A 506
ILE A 507
VAL A 542
VAL A 544
 None
 1.33A 3rf4A-1om9A:
undetectable
3rf4C-1om9A:
undetectable		 3rf4A-1om9A:
25.75
3rf4C-1om9A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 11 PRO A 503
SER A 506
ILE A 507
VAL A 542
VAL A 544
 None
 1.33A 3rf4A-1om9A:
undetectable
3rf4B-1om9A:
undetectable		 3rf4A-1om9A:
25.75
3rf4B-1om9A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_C_FUNC203_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		5 / 11 PRO A 503
SER A 506
ILE A 507
VAL A 542
VAL A 544
 None
 1.34A 3rf4B-1om9A:
undetectable
3rf4C-1om9A:
undetectable		 3rf4B-1om9A:
25.75
3rf4C-1om9A:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_C_P06C801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1om9 ADP-RIBOSYLATION
FACTOR BINDING
PROTEIN GGA1
(Homo
sapiens) 		4 / 7 VAL A 545
ILE A 592
ASN A 622
PHE A 560
 None
 0.94A 5hieC-1om9A:
0.0		 5hieC-1om9A:
21.14