SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1omo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.08A 1c8lA-1omoA:
undetectable		 1c8lA-1omoA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.09A 1gfzA-1omoA:
undetectable		 1gfzA-1omoA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.06A 1l5qA-1omoA:
0.3		 1l5qA-1omoA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.07A 1l5qB-1omoA:
undetectable		 1l5qB-1omoA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.02A 1l7xA-1omoA:
undetectable		 1l7xA-1omoA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.01A 1l7xB-1omoA:
undetectable		 1l7xB-1omoA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 131
GLY A 132
GLY A 134
VAL A 158
PRO A 196
 ILE  A 131 ( 0.7A)
GLY  A 132 ( 0.0A)
GLY  A 134 (-0.0A)
VAL  A 158 (-0.6A)
PRO  A 196 (-1.1A)
 1.07A 1nv8A-1omoA:
5.6		 1nv8A-1omoA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_B_SAMB301_0
(HEMK PROTEIN)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 131
GLY A 132
GLY A 134
VAL A 158
PRO A 196
 ILE  A 131 ( 0.7A)
GLY  A 132 ( 0.0A)
GLY  A 134 (-0.0A)
VAL  A 158 (-0.6A)
PRO  A 196 (-1.1A)
 1.02A 1nv8B-1omoA:
5.4		 1nv8B-1omoA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 8 PHE A 288
ILE A 268
ASP A 277
GLY A 278
 PHE  A 288 ( 1.3A)
ILE  A 268 ( 0.3A)
ASP  A 277 ( 0.5A)
GLY  A 278 ( 0.0A)
 0.86A 1rtsA-1omoA:
undetectable		 1rtsA-1omoA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 GLN A 140
ALA A 117
PHE A 130
ARG A 145
 GLN  A 140 ( 0.6A)
ALA  A 117 ( 0.0A)
PHE  A 130 ( 1.3A)
ARG  A 145 ( 0.6A)
 1.22A 1t9wA-1omoA:
undetectable		 1t9wA-1omoA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUL_A_SAMA376_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		3 / 3 SER A 186
GLU A 249
ASP A 219
 SER  A 186 ( 0.0A)
GLU  A 249 (-0.6A)
ASP  A 219 (-0.5A)
 0.65A 2zulA-1omoA:
5.0		 2zulA-1omoA:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 5 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.11A 3bcrA-1omoA:
undetectable		 3bcrA-1omoA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.06A 3dd1A-1omoA:
2.1		 3dd1A-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.04A 3dd1B-1omoA:
undetectable		 3dd1B-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.07A 3ddsA-1omoA:
2.2		 3ddsA-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.05A 3ddsB-1omoA:
0.0		 3ddsB-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.06A 3ddwA-1omoA:
2.4		 3ddwA-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 6 ASN A 214
PHE A 288
ALA A 117
GLY A 114
 ASN  A 214 ( 0.6A)
PHE  A 288 ( 1.3A)
ALA  A 117 ( 0.0A)
GLY  A 114 ( 0.0A)
 1.05A 3ddwB-1omoA:
undetectable		 3ddwB-1omoA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_B_SAMB300_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 GLY A 132
GLY A 134
GLN A 136
ALA A 155
LEU A 191
 GLY  A 132 ( 0.0A)
GLY  A 134 (-0.0A)
GLN  A 136 (-0.6A)
ALA  A 155 ( 0.0A)
LEU  A 191 ( 0.6A)
 1.10A 3dh0B-1omoA:
5.5		 3dh0B-1omoA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMH_A_SAMA384_1
(PROBABLE RIBOSOMAL
RNA SMALL SUBUNIT
METHYLTRANSFERASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		3 / 3 SER A 186
GLU A 249
ASP A 219
 SER  A 186 ( 0.0A)
GLU  A 249 (-0.6A)
ASP  A 219 (-0.5A)
 0.63A 3dmhA-1omoA:
5.2		 3dmhA-1omoA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA277_0
(UNIVERSAL STRESS
PROTEIN)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		3 / 3 ASP A 239
SER A 290
ARG A 108
 ASP  A 239 ( 0.5A)
SER  A 290 (-0.0A)
ARG  A 108 (-0.6A)
 0.97A 3loqA-1omoA:
4.0		 3loqA-1omoA:
24.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYR_B_RITB301_1
(HIV-1 PROTEASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 LEU A 191
ALA A 215
ILE A 259
THR A 211
 LEU  A 191 ( 0.6A)
ALA  A 215 ( 0.0A)
ILE  A 259 ( 0.6A)
THR  A 211 ( 0.8A)
 0.96A 4eyrA-1omoA:
undetectable		 4eyrA-1omoA:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVC_B_HFGB1602_0
(BIFUNCTIONAL
GLUTAMATE/PROLINE--T
RNA LIGASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   6
GLU A 306
VAL A 304
THR A  92
GLY A  93
 LEU  A   6 ( 0.6A)
GLU  A 306 ( 0.6A)
VAL  A 304 ( 0.6A)
THR  A  92 ( 0.8A)
GLY  A  93 ( 0.0A)
 1.19A 4hvcB-1omoA:
undetectable		 4hvcB-1omoA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 11 LEU A 191
ASP A 289
ILE A 236
THR A 211
ILE A 213
 LEU  A 191 ( 0.6A)
ASP  A 289 ( 0.6A)
ILE  A 236 ( 0.7A)
THR  A 211 ( 0.8A)
ILE  A 213 ( 0.7A)
 0.93A 4njtC-1omoA:
undetectable		 4njtC-1omoA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A  20
ASN A 214
ILE A 216
GLY A 114
ALA A 143
 ALA  A  20 ( 0.0A)
ASN  A 214 ( 0.6A)
ILE  A 216 (-0.7A)
GLY  A 114 ( 0.0A)
ALA  A 143 ( 0.0A)
 1.08A 4nkvA-1omoA:
undetectable		 4nkvA-1omoA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A  20
ASN A 214
ILE A 216
GLY A 114
ALA A 143
 ALA  A  20 ( 0.0A)
ASN  A 214 ( 0.6A)
ILE  A 216 (-0.7A)
GLY  A 114 ( 0.0A)
ALA  A 143 ( 0.0A)
 1.09A 4nkvC-1omoA:
undetectable		 4nkvC-1omoA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A  20
ASN A 214
ILE A 216
GLY A 114
ALA A 143
 ALA  A  20 ( 0.0A)
ASN  A 214 ( 0.6A)
ILE  A 216 (-0.7A)
GLY  A 114 ( 0.0A)
ALA  A 143 ( 0.0A)
 1.08A 4nkvD-1omoA:
undetectable		 4nkvD-1omoA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE A 288
ILE A 268
ASP A 277
GLY A 278
 PHE  A 288 ( 1.3A)
ILE  A 268 ( 0.3A)
ASP  A 277 ( 0.5A)
GLY  A 278 ( 0.0A)
 0.86A 5h3aA-1omoA:
undetectable		 5h3aA-1omoA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE A 288
ILE A 268
ASP A 277
GLY A 278
 PHE  A 288 ( 1.3A)
ILE  A 268 ( 0.3A)
ASP  A 277 ( 0.5A)
GLY  A 278 ( 0.0A)
 0.84A 5h3aB-1omoA:
0.0		 5h3aB-1omoA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI2_A_BAXA801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 8 ILE A 175
VAL A 207
ILE A 285
ASP A 189
PHE A 128
 ILE  A 175 ( 0.6A)
VAL  A 207 ( 0.6A)
ILE  A 285 ( 0.7A)
ASP  A 189 ( 0.6A)
PHE  A 128 ( 1.3A)
 1.49A 5hi2A-1omoA:
undetectable		 5hi2A-1omoA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UHB_C_RFPC1201_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 293
GLN A 296
SER A 290
ASN A 214
ILE A 216
 LEU  A 293 ( 0.6A)
GLN  A 296 ( 0.6A)
SER  A 290 (-0.0A)
ASN  A 214 ( 0.6A)
ILE  A 216 (-0.7A)
 1.21A 5uhbC-1omoA:
2.1		 5uhbC-1omoA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 ALA A 182
SER A 186
GLU A 208
LEU A 191
ILE A 213
 ALA  A 182 ( 0.0A)
SER  A 186 ( 0.0A)
GLU  A 208 ( 0.6A)
LEU  A 191 ( 0.6A)
ILE  A 213 ( 0.7A)
 1.50A 5vlmA-1omoA:
0.0		 5vlmA-1omoA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   6
GLU A 306
VAL A 304
THR A  92
GLY A  93
 LEU  A   6 ( 0.6A)
GLU  A 306 ( 0.6A)
VAL  A 304 ( 0.6A)
THR  A  92 ( 0.8A)
GLY  A  93 ( 0.0A)
 1.22A 5xipA-1omoA:
undetectable		 5xipA-1omoA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   6
GLU A 306
VAL A 304
THR A  92
GLY A  93
 LEU  A   6 ( 0.6A)
GLU  A 306 ( 0.6A)
VAL  A 304 ( 0.6A)
THR  A  92 ( 0.8A)
GLY  A  93 ( 0.0A)
 1.29A 5xipC-1omoA:
undetectable		 5xipC-1omoA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_A_HFGA1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   6
GLU A 306
VAL A 304
THR A  92
GLY A  93
 LEU  A   6 ( 0.6A)
GLU  A 306 ( 0.6A)
VAL  A 304 ( 0.6A)
THR  A  92 ( 0.8A)
GLY  A  93 ( 0.0A)
 1.20A 5xiqA-1omoA:
undetectable		 5xiqA-1omoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A   6
GLU A 306
VAL A 304
THR A  92
GLY A  93
 LEU  A   6 ( 0.6A)
GLU  A 306 ( 0.6A)
VAL  A 304 ( 0.6A)
THR  A  92 ( 0.8A)
GLY  A  93 ( 0.0A)
 1.16A 5xiqD-1omoA:
undetectable		 5xiqD-1omoA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_C_EU7C101_0
(MATRIX PROTEIN 2)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		5 / 9 ALA A  97
VAL A 304
ALA A 308
VAL A  11
GLY A 314
 ALA  A  97 ( 0.0A)
VAL  A 304 ( 0.6A)
ALA  A 308 ( 0.0A)
VAL  A  11 ( 0.6A)
GLY  A 314 ( 0.0A)
 1.20A 6bklA-1omoA:
undetectable
6bklB-1omoA:
undetectable
6bklC-1omoA:
undetectable
6bklD-1omoA:
undetectable		 6bklA-1omoA:
5.81
6bklB-1omoA:
5.81
6bklC-1omoA:
5.81
6bklD-1omoA:
5.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 ALA A 101
THR A 102
TYR A 103
GLN A 296
 ALA  A 101 ( 0.0A)
THR  A 102 ( 0.8A)
TYR  A 103 ( 1.3A)
GLN  A 296 ( 0.6A)
 0.68A 6cduA-1omoA:
0.0
6cduE-1omoA:
0.0		 6cduA-1omoA:
22.70
6cduE-1omoA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 8 GLN A 296
ALA A 101
THR A 102
TYR A 103
 GLN  A 296 ( 0.6A)
ALA  A 101 ( 0.0A)
THR  A 102 ( 0.8A)
TYR  A 103 ( 1.3A)
 0.74A 6cduD-1omoA:
undetectable
6cduE-1omoA:
undetectable		 6cduD-1omoA:
22.70
6cduE-1omoA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		4 / 7 GLN A 296
ALA A 101
THR A 102
TYR A 103
 GLN  A 296 ( 0.6A)
ALA  A 101 ( 0.0A)
THR  A 102 ( 0.8A)
TYR  A 103 ( 1.3A)
 0.67A 6cduH-1omoA:
undetectable
6cduI-1omoA:
undetectable		 6cduH-1omoA:
22.70
6cduI-1omoA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GB9_A_ACTA508_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 1omo ALANINE
DEHYDROGENASE
(Archaeoglobus
fulgidus) 		3 / 3 VAL A  24
ALA A 111
GLN A 296
 VAL  A  24 ( 0.6A)
ALA  A 111 ( 0.0A)
GLN  A 296 ( 0.6A)
 0.62A 6gb9A-1omoA:
undetectable		 6gb9A-1omoA:
23.68