SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1on0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		4 / 5 ALA A 131
ALA A  31
LYS A  30
GLU A  27
 None
 1.12A 1e7cA-1on0A:
undetectable		 1e7cA-1on0A:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A   3
ALA A 112
LEU A  76
ALA A 116
LEU A  96
 None
None
None
None
SO4  A 401 (-4.8A)
 0.96A 1fm9A-1on0A:
undetectable		 1fm9A-1on0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A   3
ALA A 112
LEU A  76
ALA A 116
LEU A  96
 None
None
None
None
SO4  A 401 (-4.8A)
 0.96A 1xiuB-1on0A:
undetectable		 1xiuB-1on0A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		4 / 7 ASP A  93
PHE A  94
GLY A  74
THR A  20
 None
 0.98A 3vnsA-1on0A:
undetectable		 3vnsA-1on0A:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_A_ADNA501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		3 / 3 PRO A  52
LEU A  51
HIS A  61
 None
 0.68A 4pevA-1on0A:
undetectable		 4pevA-1on0A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_A_4LEA401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		5 / 8 LEU A 125
ALA A  89
LEU A  76
LEU A 113
ALA A 117
 None
 1.15A 4z90A-1on0A:
undetectable
4z90B-1on0A:
0.0
4z90C-1on0A:
0.0
4z90D-1on0A:
0.0
4z90E-1on0A:
0.0		 4z90A-1on0A:
18.07
4z90B-1on0A:
18.07
4z90C-1on0A:
18.07
4z90D-1on0A:
18.07
4z90E-1on0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF402_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		5 / 7 LEU A 113
ALA A 117
LEU A 125
ALA A  89
LEU A  76
 None
 1.08A 4z90F-1on0A:
undetectable
4z90G-1on0A:
undetectable
4z90H-1on0A:
undetectable
4z90J-1on0A:
undetectable		 4z90F-1on0A:
18.07
4z90G-1on0A:
18.07
4z90H-1on0A:
18.07
4z90J-1on0A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A 139
ALA A 136
LEU A 110
 None
 0.52A 5uunB-1on0A:
undetectable		 5uunB-1on0A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1on0 YYCN PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A   3
ALA A 112
LEU A  76
ALA A 116
LEU A  96
 None
None
None
None
SO4  A 401 (-4.8A)
 1.03A 6a60D-1on0A:
undetectable		 6a60D-1on0A:
19.62