SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA501_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 7 TYR A  21
ILE A  37
PRO A 116
GLU A 122
 None
 0.41A 1oniA-1oniA:
29.1
1oniB-1oniA:
26.7		 1oniA-1oniA:
100.00
1oniB-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 6 PHE A  89
ASN A  90
ASN A  93
ARG A 107
 BEZ  A 502 ( 3.6A)
None
BEZ  A 502 (-3.1A)
BEZ  A 501 ( 3.6A)
 0.97A 1oniA-1oniA:
29.1
1oniB-1oniA:
26.7		 1oniA-1oniA:
100.00
1oniB-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 6 TYR A  21
ILE A  37
PRO A 116
GLU A 122
 None
 0.36A 1oniB-1oniA:
26.7
1oniC-1oniA:
26.6		 1oniB-1oniA:
100.00
1oniC-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_C_BEZC505_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 6 TYR A  21
ILE A  37
PRO A 116
GLU A 122
 None
 0.01A 1oniA-1oniA:
29.1
1oniC-1oniA:
26.6		 1oniA-1oniA:
100.00
1oniC-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 6 PHE A  89
ASN A  90
ASN A  93
ARG A 107
 BEZ  A 502 ( 3.6A)
None
BEZ  A 502 (-3.1A)
BEZ  A 501 ( 3.6A)
 0.99A 1oniD-1oniA:
27.1
1oniF-1oniA:
26.5		 1oniD-1oniA:
100.00
1oniF-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_E_BEZE509_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 7 TYR A  21
ILE A  37
PRO A 116
GLU A 122
 None
 0.25A 1oniD-1oniA:
27.1
1oniE-1oniA:
26.8		 1oniD-1oniA:
100.00
1oniE-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI517_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 7 TYR A  21
ILE A  37
PRO A 116
GLU A 122
 None
 0.45A 1oniG-1oniA:
26.3
1oniI-1oniA:
27.3		 1oniG-1oniA:
100.00
1oniI-1oniA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ONI_I_BEZI518_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		4 / 7 PHE A  89
ASN A  90
ASN A  93
ARG A 107
 BEZ  A 502 ( 3.6A)
None
BEZ  A 502 (-3.1A)
BEZ  A 501 ( 3.6A)
 0.44A 1oniG-1oniA:
26.3
1oniI-1oniA:
27.3		 1oniG-1oniA:
100.00
1oniI-1oniA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		3 / 3 ILE A  33
ILE A  31
THR A  79
 None
 0.65A 1rg7A-1oniA:
undetectable		 1rg7A-1oniA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_2
(PROTEASE)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 11 GLY A  70
ALA A  69
ILE A  65
GLY A  63
ILE A  31
 None
 0.82A 2r5qB-1oniA:
undetectable		 2r5qB-1oniA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_2
(PROTEASE)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 10 GLY A  70
ALA A  69
ILE A  65
GLY A  63
ILE A  31
 None
 0.82A 2r5qD-1oniA:
undetectable		 2r5qD-1oniA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  81
LEU A  83
VAL A  51
ALA A  55
LEU A  59
 None
 1.17A 4rrwA-1oniA:
undetectable		 4rrwA-1oniA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  81
LEU A  83
VAL A  51
ALA A  55
LEU A  59
 None
 1.18A 4rrwB-1oniA:
undetectable		 4rrwB-1oniA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  81
LEU A  83
VAL A  51
ALA A  55
LEU A  59
 None
 1.17A 4rrzA-1oniA:
undetectable		 4rrzA-1oniA:
12.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1oni 14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN
(Homo
sapiens) 		5 / 12 VAL A  81
LEU A  83
VAL A  51
ALA A  55
LEU A  59
 None
 1.18A 4rrzB-1oniA:
undetectable		 4rrzB-1oniA:
12.27