SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1onk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XOQ_A_ROFA502_1 (CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	3 / 3	ASN B 156 TRP B 161 GLN B 169	None	1.41A	1xoqA-1onkB: undetectable	1xoqA-1onkB: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2DCF_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	4 / 6	ALA B 233 TRP B 259 ILE B 225 ILE B 248	None	1.06A	2dcfA-1onkB: undetectable	2dcfA-1onkB: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM7_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	4 / 7	ALA B 233 TRP B 259 ILE B 225 ILE B 248	None	1.05A	2zm7A-1onkB: 0.0	2zm7A-1onkB: 19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM8_A_ACAA511_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	4 / 8	ALA B 233 TRP B 259 ILE B 225 ILE B 248	None	1.03A	2zm8A-1onkB: undetectable	2zm8A-1onkB: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMA_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	4 / 8	ALA B 233 TRP B 259 ILE B 225 ILE B 248	None	1.03A	2zmaA-1onkB: undetectable	2zmaA-1onkB: 20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R24_A_SAMA302_0 (2'-O-METHYL TRANSFERASE)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	5 / 12	ASN B 18 GLY B 131 SER B 181 GLY B 19 LEU B 228	None None None None NAG B5002 ( 4.7A)	1.27A	3r24A-1onkB: undetectable	3r24A-1onkB: 24.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0Y_A_FOLA201_1 (CONSERVED HYPOTHETICAL MEMBRANE PROTEIN)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	3 / 3	ARG B 54 LYS B 53 GLU B 9	None	0.72A	5d0yA-1onkB: undetectable	5d0yA-1onkB: 19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5U6N_A_SALA505_1 (UDP-GLYCOSYLTRANSFER ASE 74F2)	1onk	GALACTOSE SPECIFIC LECTIN I B CHAIN (Viscum album)	4 / 8	SER B 104 GLN B 130 TRP B 94 THR B 98	None None NAG B5002 (-4.2A) None	1.42A	5u6nA-1onkB: undetectable	5u6nA-1onkB: 18.79

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1XOQ_A_ROFA502_1","CAMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE 4D","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",3,"ASN B 156;TRP B 161;GLN B 169","None","1.41A","1xoqA-1onkB:undetectable","1xoqA-1onkB:21.69"],["2DCF_A_ACAA501_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",4,"ALA B 233;TRP B 259;ILE B 225;ILE B 248","None","1.06A","2dcfA-1onkB:undetectable","2dcfA-1onkB:20.60"],["2ZM7_A_ACAA501_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",4,"ALA B 233;TRP B 259;ILE B 225;ILE B 248","None","1.05A","2zm7A-1onkB:0.0","2zm7A-1onkB:19.65"],["2ZM8_A_ACAA511_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",4,"ALA B 233;TRP B 259;ILE B 225;ILE B 248","None","1.03A","2zm8A-1onkB:undetectable","2zm8A-1onkB:21.01"],["2ZMA_A_ACAA501_1","6-AMINOHEXANOATE-DIMER HYDROLASE","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",4,"ALA B 233;TRP B 259;ILE B 225;ILE B 248","None","1.03A","2zmaA-1onkB:undetectable","2zmaA-1onkB:20.60"],["3R24_A_SAMA302_0","2'-O-METHYL TRANSFERASE","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",5,"ASN B  18;GLY B 131;SER B 181;GLY B  19;LEU B 228","None;None;None;None;NAG B5002 ( 4.7A)","1.27A","3r24A-1onkB:undetectable","3r24A-1onkB:24.86"],["5D0Y_A_FOLA201_1","CONSERVED HYPOTHETICAL MEMBRANE PROTEIN","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",3,"ARG B  54;LYS B  53;GLU B   9","None","0.72A","5d0yA-1onkB:undetectable","5d0yA-1onkB:19.56"],["5U6N_A_SALA505_1","UDP-GLYCOSYLTRANSFERASE 74F2","1onk","GALACTOSE SPECIFIC LECTIN I B CHAIN","Viscum album",4,"SER B 104;GLN B 130;TRP B  94;THR B  98","None;None;NAG B5002 (-4.2A);None","1.42A","5u6nA-1onkB:undetectable","5u6nA-1onkB:18.79"]]