SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1onl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 111
ILE A  76
ARG A  48
VAL A  25
 None
 0.96A 1db1A-1onlA:
0.0		 1db1A-1onlA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		4 / 7 ILE A   3
PRO A   4
GLY A  96
GLN A  92
 None
 0.94A 4g0uB-1onlA:
undetectable		 4g0uB-1onlA:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		4 / 8 ALA A  31
ASP A  29
GLY A  36
ILE A  27
 None
 0.76A 4ll3A-1onlA:
undetectable		 4ll3A-1onlA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		4 / 5 TYR A   9
LEU A  24
ASP A  93
VAL A  41
 None
 1.21A 4nkvA-1onlA:
undetectable		 4nkvA-1onlA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		4 / 5 ALA A  31
THR A  28
TYR A  95
HIS A  13
 None
 1.39A 5ecmA-1onlA:
undetectable		 5ecmA-1onlA:
12.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1onl GLYCINE CLEAVAGE
SYSTEM H PROTEIN
(Thermus
thermophilus) 		5 / 12 ILE A 100
ALA A  55
VAL A  58
ILE A  68
PRO A  44
 None
 1.30A 5mlmA-1onlA:
undetectable		 5mlmA-1onlA:
16.03