SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oow'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTV_A_TESA500_1
(17
BETA-HYDROXYSTEROID
DEHYDROGENASE TYPE 1)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 8 VAL A  96
LEU A  74
SER A  56
VAL A  39
 None
 0.94A 1jtvA-1oowA:
undetectable		 1jtvA-1oowA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 7 PHE A  29
PHE A  82
PHE A  41
VAL A   1
 None
 0.96A 1lh6A-1oowA:
undetectable		 1lh6A-1oowA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.44A 1oe1A-1oowA:
undetectable		 1oe1A-1oowA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		5 / 5 HIS A  37
CYH A  84
PRO A  86
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 ( 4.9A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.79A 1oe2A-1oowA:
6.4		 1oe2A-1oowA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.47A 1oe3A-1oowA:
undetectable		 1oe3A-1oowA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.33A 2fqdA-1oowA:
undetectable		 2fqdA-1oowA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.32A 2fqeA-1oowA:
undetectable		 2fqeA-1oowA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.32A 2fqfA-1oowA:
undetectable		 2fqfA-1oowA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.30A 2fqgA-1oowA:
undetectable		 2fqgA-1oowA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.43A 2xxgA-1oowA:
5.6		 2xxgA-1oowA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		5 / 5 HIS A  37
CYH A  84
PRO A  86
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 ( 4.9A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.84A 2xxgC-1oowA:
5.5		 2xxgC-1oowA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 4 HIS A  37
CYH A  84
HIS A  87
MET A  92
 CU  A 100 (-3.1A)
CU  A 100 (-2.2A)
CU  A 100 (-3.2A)
CU  A 100 (-2.8A)
 0.28A 4ef3A-1oowA:
undetectable		 4ef3A-1oowA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 5 GLU A  25
VAL A  21
VAL A   3
PHE A  19
 None
 1.05A 4lb0B-1oowA:
undetectable		 4lb0B-1oowA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1oow PLASTOCYANIN,
CHLOROPLAST
(Spinacia
oleracea) 		4 / 8 TYR A  80
PHE A  41
PHE A  29
VAL A  21
 None
 1.01A 6huoC-1oowA:
1.0
6huoD-1oowA:
undetectable		 6huoC-1oowA:
21.36
6huoD-1oowA:
21.57