SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1op9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_C_377C401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1op9	HL6 CAMEL VHH FRAGMENT (Camelus dromedarius)	4 / 6	ASN A 74 GLU A 97 TYR A 110 LEU A 4	None	1.11A	4twdB-1op9A: undetectable 4twdC-1op9A: undetectable	4twdB-1op9A: 15.64 4twdC-1op9A: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_E_377E401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1op9	HL6 CAMEL VHH FRAGMENT (Camelus dromedarius)	4 / 6	ASN A 74 GLU A 97 TYR A 110 LEU A 4	None	1.16A	4twdD-1op9A: 2.3 4twdE-1op9A: 1.2	4twdD-1op9A: 15.64 4twdE-1op9A: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECM_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1op9	HL6 CAMEL VHH FRAGMENT (Camelus dromedarius)	4 / 7	ALA A 89 THR A 88 VAL A 117 GLU A 86	None	0.73A	5ecmD-1op9A: undetectable	5ecmD-1op9A: 13.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	1op9	HL6 CAMEL VHH FRAGMENT (Camelus dromedarius)	4 / 7	ALA A 89 THR A 88 VAL A 117 GLU A 86	None	0.82A	5ecoD-1op9A: undetectable	5ecoD-1op9A: 13.24

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4TWD_C_377C401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","1op9","HL6 CAMEL VHH FRAGMENT","Camelus dromedarius",4,"ASN A  74;GLU A  97;TYR A 110;LEU A   4","None","1.11A","4twdB-1op9A:undetectable;4twdC-1op9A:undetectable","4twdB-1op9A:15.64;4twdC-1op9A:15.64"],["4TWD_E_377E401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","1op9","HL6 CAMEL VHH FRAGMENT","Camelus dromedarius",4,"ASN A  74;GLU A  97;TYR A 110;LEU A   4","None","1.16A","4twdD-1op9A:2.3;4twdE-1op9A:1.2","4twdD-1op9A:15.64;4twdE-1op9A:15.64"],["5ECM_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1op9","HL6 CAMEL VHH FRAGMENT","Camelus dromedarius",4,"ALA A  89;THR A  88;VAL A 117;GLU A  86","None","0.73A","5ecmD-1op9A:undetectable","5ecmD-1op9A:13.24"],["5ECO_D_LEUD602_0","JASMONIC ACID-AMIDO SYNTHETASE JAR1","1op9","HL6 CAMEL VHH FRAGMENT","Camelus dromedarius",4,"ALA A  89;THR A  88;VAL A 117;GLU A  86","None","0.82A","5ecoD-1op9A:undetectable","5ecoD-1op9A:13.24"]]