SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1opc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUG_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1opc OMPR
(Escherichia
coli) 		5 / 12 GLY A 164
VAL A 203
GLY A 191
ALA A 189
ASP A 183
 None
 1.04A 3sugA-1opcA:
undetectable		 3sugA-1opcA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 1opc OMPR
(Escherichia
coli) 		4 / 5 VAL A 212
LEU A 169
VAL A 173
PHE A 140
 None
 0.91A 4lb0B-1opcA:
undetectable		 4lb0B-1opcA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA810_0
(GEPHYRIN)		 1opc OMPR
(Escherichia
coli) 		3 / 3 LEU A 161
SER A 163
PHE A 166
 None
 0.54A 6fgcA-1opcA:
undetectable		 6fgcA-1opcA:
13.46