SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1opo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1opo COAT PROTEIN
(Carnation
mottle
virus) 		3 / 3 SER A 257
ASP A 210
ASP A 158
 None
 0.91A 3uj7A-1opoA:
undetectable		 3uj7A-1opoA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_1
(DIHYDROFOLATE
REDUCTASE)		 1opo COAT PROTEIN
(Carnation
mottle
virus) 		5 / 12 ALA A 159
ASP A 192
ARG A 196
LEU A 135
ILE A 214
 None
 0.79A 4m2xA-1opoA:
undetectable		 4m2xA-1opoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_E_TMQE202_1
(DIHYDROFOLATE
REDUCTASE)		 1opo COAT PROTEIN
(Carnation
mottle
virus) 		5 / 12 ALA A 159
ASP A 192
ARG A 196
LEU A 135
ILE A 214
 None
 0.86A 4m2xE-1opoA:
undetectable		 4m2xE-1opoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1opo COAT PROTEIN
(Carnation
mottle
virus) 		4 / 8 PRO A 297
LEU A 330
VAL A 345
LEU A 321
 None
 1.01A 4pwdA-1opoA:
undetectable		 4pwdA-1opoA:
21.75