SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P33_B_MTXB352_1
(PTERIDINE REDUCTASE
1)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		5 / 12 SER A 156
PHE A  66
TYR A 116
LEU A  39
LEU A  37
 None
 1.42A 1p33B-1oq1A:
0.0		 1p33B-1oq1A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDY_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		5 / 12 SER A  17
VAL A  19
GLN A 201
ILE A  30
PHE A  50
 None
 1.44A 2vdyA-1oq1A:
0.0		 2vdyA-1oq1A:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_2
(GLUCOCORTICOID
RECEPTOR)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		3 / 3 MET A 160
CYH A  75
PRO A  68
 None
 1.00A 3h52C-1oq1A:
undetectable		 3h52C-1oq1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		5 / 12 LEU A  94
ALA A  81
GLY A 195
GLY A  83
ASP A 108
 None
 0.97A 3ou7D-1oq1A:
undetectable		 3ou7D-1oq1A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		5 / 12 SER A  17
VAL A  19
GLN A 201
ILE A  30
PHE A  50
 None
 1.44A 4c49C-1oq1A:
undetectable		 4c49C-1oq1A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		3 / 3 PHE A  78
VAL A  49
GLU A  25
 None
 0.78A 4fvqA-1oq1A:
0.0		 4fvqA-1oq1A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		4 / 7 PRO A  12
ASP A  18
SER A  15
SER A  17
 None
 1.23A 4k7gB-1oq1A:
0.0		 4k7gB-1oq1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1oq1 PROTEIN YESU
(Bacillus
subtilis) 		4 / 4 GLY A 167
VAL A 169
PHE A  56
ILE A  60
 None
 1.15A 4xv2B-1oq1A:
undetectable		 4xv2B-1oq1A:
22.37