SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oqa'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_A_DVAA6_0
(MINI-GRAMICIDIN A)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A  90
VAL A  85
TRP A  84
 None
 0.81A 1kqeA-1oqaA:
undetectable
1kqeE-1oqaA:
undetectable		 1kqeA-1oqaA:
10.29
1kqeE-1oqaA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_B_DVAB6_0
(MINI-GRAMICIDIN A)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 ALA A  90
VAL A  85
TRP A  84
 None
 0.79A 1kqeB-1oqaA:
undetectable
1kqeD-1oqaA:
undetectable		 1kqeB-1oqaA:
10.29
1kqeD-1oqaA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_D_DVAD6_0
(MINI-GRAMICIDIN A)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 TRP A  84
ALA A  90
VAL A  85
 None
 0.81A 1kqeB-1oqaA:
undetectable
1kqeD-1oqaA:
undetectable		 1kqeB-1oqaA:
10.29
1kqeD-1oqaA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQE_E_DVAE6_0
(MINI-GRAMICIDIN A)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 TRP A  84
ALA A  90
VAL A  85
 None
 0.81A 1kqeA-1oqaA:
undetectable
1kqeE-1oqaA:
undetectable		 1kqeA-1oqaA:
10.29
1kqeE-1oqaA:
10.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 GLY A  17
PRO A  18
GLN A  58
 None
 0.59A 4qwpB-1oqaA:
0.0		 4qwpB-1oqaA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 1oqa BREAST CANCER TYPE 1
SUSCEPTIBILITY
PROTEIN
(Homo
sapiens) 		3 / 3 VAL A  79
GLN A  73
CYH A  75
 None
 0.76A 5icxA-1oqaA:
0.0
5icxE-1oqaA:
undetectable		 5icxA-1oqaA:
21.11
5icxE-1oqaA:
20.00