SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oqv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 11 SER A  75
VAL A  74
GLY A  72
GLY A  77
TYR A  51
 None
 1.31A 1iolA-1oqvA:
undetectable		 1iolA-1oqvA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UDU_A_CIAA1003_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 11 VAL A 194
ALA A 195
PHE A 196
LEU A  40
PHE A  88
 None
 1.24A 1uduA-1oqvA:
undetectable		 1uduA-1oqvA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		4 / 4 LEU A 115
ILE A 124
GLY A 193
PHE A 196
 None
 1.11A 4dc3A-1oqvA:
undetectable		 4dc3A-1oqvA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJF_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 12 PHE A  88
ILE A 164
GLY A 128
SER A 126
ILE A 124
 None
 1.39A 4djfA-1oqvA:
undetectable		 4djfA-1oqvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		4 / 8 LYS A  35
ALA A  36
LEU A  40
LEU A 123
 None
 0.84A 4po0A-1oqvA:
undetectable		 4po0A-1oqvA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		4 / 7 THR A  64
ALA A  61
THR A  60
ALA A  59
 None
 0.78A 4qw0K-1oqvA:
undetectable		 4qw0K-1oqvA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		4 / 7 THR A  64
ALA A  61
THR A  60
ALA A  59
 None
 0.79A 4qw0Y-1oqvA:
undetectable		 4qw0Y-1oqvA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		3 / 3 ASN A 105
PHE A 108
TYR A 133
 None
 0.89A 4u15A-1oqvA:
undetectable		 4u15A-1oqvA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 10 GLY A 193
VAL A 194
VAL A 112
LEU A 147
LEU A  40
 None
 1.11A 4yb6A-1oqvA:
undetectable
4yb6E-1oqvA:
undetectable		 4yb6A-1oqvA:
20.20
4yb6E-1oqvA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 10 GLY A 193
VAL A 194
VAL A 112
LEU A 147
LEU A  40
 None
 1.12A 4yb6B-1oqvA:
undetectable
4yb6C-1oqvA:
undetectable		 4yb6B-1oqvA:
20.20
4yb6C-1oqvA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 1oqv TOXIN-COREGULATED
PILUS SUBUNIT
(Vibrio
cholerae) 		5 / 10 LEU A 147
LEU A  40
GLY A 193
VAL A 194
VAL A 112
 None
 1.11A 4yb6B-1oqvA:
undetectable
4yb6F-1oqvA:
undetectable		 4yb6B-1oqvA:
20.20
4yb6F-1oqvA:
20.20