SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ors'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_A_AG2A7005_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 1.03A 1mt1A-1orsB:
0.0
1mt1F-1orsB:
undetectable		 1mt1A-1orsB:
11.06
1mt1F-1orsB:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MT1_B_AG2B7001_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 ILE B  68
ARG B  67
ASP B  90
LEU B  18
 None
 1.01A 1mt1B-1orsB:
0.0
1mt1C-1orsB:
0.0		 1mt1B-1orsB:
19.05
1mt1C-1orsB:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_L_AG2L7014_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 1.01A 1n13I-1orsB:
undetectable
1n13L-1orsB:
0.0		 1n13I-1orsB:
11.06
1n13L-1orsB:
19.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1RUK_H_BEZH601_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 8 ALA B  34
ASN B  36
TRP B  48
TYR B  51
 None
 0.28A 1rukH-1orsB:
26.4
1rukL-1orsB:
17.2		 1rukH-1orsB:
83.41
1rukL-1orsB:
27.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_A_HSMA401_1
(NITROPHORIN 1)		 1ors POTASSIUM CHANNEL
(Aeropyrum
pernix) 		4 / 4 ASP C  62
LEU C  69
LEU C  97
LEU C  65
 None
 1.31A 1u18A-1orsC:
undetectable		 1u18A-1orsC:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ILE B  68
ARG B  67
ASP B  90
LEU B  18
 None
 0.98A 2qqcB-1orsB:
undetectable
2qqcC-1orsB:
0.0		 2qqcB-1orsB:
19.52
2qqcC-1orsB:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_A_AG2A672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 0.98A 2qqcA-1orsB:
0.0
2qqcF-1orsB:
undetectable		 2qqcA-1orsB:
11.06
2qqcF-1orsB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 0.99A 2qqcG-1orsB:
0.0
2qqcJ-1orsB:
0.0		 2qqcG-1orsB:
11.06
2qqcJ-1orsB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQC_I_AG2I672_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 0.97A 2qqcI-1orsB:
0.0
2qqcL-1orsB:
undetectable		 2qqcI-1orsB:
11.06
2qqcL-1orsB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQD_A_AG2A671_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE (EC
4.1.1.19) (PVLARGDC))		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 7 ASP B  90
LEU B  18
ILE B  68
ARG B  67
 None
 1.00A 2qqdA-1orsB:
0.0
2qqdE-1orsB:
0.0		 2qqdA-1orsB:
11.54
2qqdE-1orsB:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		4 / 6 CYH B 200
THR B 199
CYH B 145
GLY B 144
 None
 1.22A 3w9tE-1orsB:
undetectable		 3w9tE-1orsB:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQI_A_NIOA403_1
(NICOTINATE-NUCLEOTID
E--DIMETHYLBENZIMIDA
ZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 9 GLY B 111
GLY B   8
LEU B  20
GLU B   6
GLY B  10
 None
 1.26A 4kqiA-1orsB:
undetectable		 4kqiA-1orsB:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZY_A_SAMA603_0
(LEGIONELLA EFFECTOR
LEGAS4)		 1ors 33H1 FAB HEAVY CHAIN
(Mus
musculus) 		5 / 12 GLY B  99
TYR B  51
PHE B  95
TYR B 107
LEU B   4
 None
 1.24A 5czyA-1orsB:
undetectable		 5czyA-1orsB:
18.08