SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 8 GLY A 124
SER A 110
ILE A 163
LEU A 121
 None
 0.91A 1jg4A-1oruA:
undetectable		 1jg4A-1oruA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB201_1
(PROTEIN S100-A4)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 8 GLY A  99
ILE A 160
PHE A  30
PHE A 114
 None
 0.88A 3ko0B-1oruA:
0.0
3ko0J-1oruA:
0.0		 3ko0B-1oruA:
19.58
3ko0J-1oruA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ201_1
(PROTEIN S100-A4)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 8 PHE A  30
GLY A 168
ILE A 112
CYH A 162
 None
 0.94A 3ko0O-1oruA:
undetectable
3ko0Q-1oruA:
0.0		 3ko0O-1oruA:
19.58
3ko0Q-1oruA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A  35
PHE A  30
ALA A  15
THR A  22
LEU A  12
 None
 1.21A 3s79A-1oruA:
undetectable		 3s79A-1oruA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		5 / 9 ALA A 149
ILE A 136
GLY A 133
ILE A 130
LEU A 155
 None
 1.07A 3u7sA-1oruA:
undetectable		 3u7sA-1oruA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5O_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 PHE A  30
PRO A 167
VAL A 164
ALA A 118
 None
 1.31A 4w5oA-1oruA:
undetectable		 4w5oA-1oruA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 PHE A  30
PRO A 167
VAL A 164
ALA A 118
 None
 1.27A 4z4cA-1oruA:
undetectable		 4z4cA-1oruA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4D_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 PHE A  30
PRO A 167
VAL A 164
ALA A 118
 None
 1.32A 4z4dA-1oruA:
undetectable		 4z4dA-1oruA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4E_A_IPHA906_0
(PROTEIN ARGONAUTE-2)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 PHE A  30
PRO A 167
VAL A 164
ALA A 118
 None
 1.31A 4z4eA-1oruA:
undetectable		 4z4eA-1oruA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.17A 5hm8A-1oruA:
undetectable		 5hm8A-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.17A 5hm8B-1oruA:
undetectable		 5hm8B-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.18A 5hm8C-1oruA:
undetectable		 5hm8C-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.17A 5hm8D-1oruA:
undetectable		 5hm8D-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.17A 5hm8E-1oruA:
undetectable		 5hm8E-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.17A 5hm8F-1oruA:
undetectable		 5hm8F-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.25A 5hm8G-1oruA:
undetectable		 5hm8G-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 GLU A  10
GLU A  89
THR A  22
LEU A  28
 None
 1.18A 5hm8H-1oruA:
undetectable		 5hm8H-1oruA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		5 / 10 GLY A  34
ALA A 118
VAL A 164
ASP A  38
ILE A  66
 None
 1.17A 5i3cB-1oruA:
undetectable		 5i3cB-1oruA:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		5 / 12 ILE A  35
PHE A  30
ALA A  15
THR A  22
LEU A  12
 None
 1.19A 5jkvA-1oruA:
undetectable		 5jkvA-1oruA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LW1_H_ADNH401_1
(MITOGEN-ACTIVATED
PROTEIN KINASE 8)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		5 / 9 GLY A  34
VAL A 164
ALA A 118
ASN A  94
VAL A  95
 None
 1.06A 5lw1H-1oruA:
undetectable		 5lw1H-1oruA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 8 ILE A 176
ILE A  66
THR A  22
LEU A  12
 None
 0.68A 5og9A-1oruA:
undetectable		 5og9A-1oruA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 4 VAL A 164
GLY A  34
ASP A  31
ASP A  29
 None
 1.26A 6cjkC-1oruA:
undetectable		 6cjkC-1oruA:
19.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 6 ASN A 126
ASP A 127
ARG A  63
ARG A  50
 CL  A 506 ( 4.8A)
None
None
CL  A 506 ( 4.0A)
 1.06A 6dwdA-1oruA:
undetectable
6dwdC-1oruA:
undetectable		 6dwdA-1oruA:
17.23
6dwdC-1oruA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 ASN A 126
ASP A 127
ARG A  63
ARG A  50
 CL  A 506 ( 4.8A)
None
None
CL  A 506 ( 4.0A)
 1.07A 6dwdB-1oruA:
undetectable
6dwdD-1oruA:
undetectable		 6dwdB-1oruA:
17.23
6dwdD-1oruA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1oru YUAD PROTEIN
(Bacillus
subtilis) 		4 / 5 ARG A  63
ARG A  50
ASN A 126
ASP A 127
 None
CL  A 506 ( 4.0A)
CL  A 506 ( 4.8A)
None
 1.10A 6dwjB-1oruA:
undetectable
6dwjD-1oruA:
undetectable		 6dwjB-1oruA:
17.23
6dwjD-1oruA:
17.23