SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1osc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HRD_B_NIOB5661_1
(NICOTINATE
DEHYDROGENASE LARGE
MOLYBDOPTERIN
SUBUNIT
NICOTINATE
DEHYDROGENASE MEDIUM
MOLYBDOPTERIN
SUBUNIT)		 1osc SIMILAR TO DIVALENT
CATION TOLERANT
PROTEIN CUTA
(Rattus
norvegicus) 		4 / 8 ILE A  27
ARG A  81
THR A  77
LEU A  76
 None
 0.87A 3hrdA-1oscA:
undetectable
3hrdB-1oscA:
undetectable		 3hrdA-1oscA:
14.78
3hrdB-1oscA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1osc SIMILAR TO DIVALENT
CATION TOLERANT
PROTEIN CUTA
(Rattus
norvegicus) 		3 / 3 PHE A  15
VAL A  31
ILE A  27
 None
 0.53A 4emaA-1oscA:
undetectable		 4emaA-1oscA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 1osc SIMILAR TO DIVALENT
CATION TOLERANT
PROTEIN CUTA
(Rattus
norvegicus) 		4 / 8 ILE A  27
ALA A  14
VAL A  91
VAL A  31
 None
 0.76A 5ecnD-1oscA:
undetectable		 5ecnD-1oscA:
12.35