SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ose'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 TYR A  62
LEU A 162
LEU A 165
ASP A 197
ALA A 198
HIS A 299
ASP A 300
 AC1  A 992 ( 3.6A)
None
AC1  A 990 ( 4.8A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.61A 1dedA-1oseA:
27.3		 1dedA-1oseA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		8 / 12 TYR A  62
LEU A 165
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 AC1  A 992 ( 3.6A)
AC1  A 990 ( 4.8A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.70A 1dedB-1oseA:
24.9		 1dedB-1oseA:
24.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 TYR A  62
GLN A  63
HIS A 201
GLU A 233
HIS A 299
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
 1.14A 1eswA-1oseA:
14.1		 1eswA-1oseA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA651_1
(AMYLOMALTASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 TYR A  62
GLN A  63
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 1.01A 1eswA-1oseA:
14.1		 1eswA-1oseA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		3 / 3 ASN A  87
PHE A  79
VAL A 191
 None
 0.84A 1kijA-1oseA:
undetectable		 1kijA-1oseA:
22.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		10 / 12 TRP A  58
GLN A  63
HIS A 101
VAL A 163
GLY A 164
ALA A 198
GLU A 233
ILE A 235
ASP A 300
HIS A 305
 None
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.7A)
AC1  A 990 (-4.3A)
AC1  A 990 (-3.5A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
BGC  A 993 (-3.9A)
AC1  A 992 (-3.0A)
GLC  A 991 ( 4.0A)
 0.46A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
HIS A 101
GLY A 104
GLU A 233
ASP A 300
HIS A 305
 None
AC1  A 992 ( 3.7A)
AC1  A 990 ( 3.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 (-3.0A)
GLC  A 991 ( 4.0A)
 1.21A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KXH_A_ACRA598_2
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		3 / 3 TRP A  59
TYR A  62
LEU A 165
 AC1  A 990 ( 3.9A)
AC1  A 992 ( 3.6A)
AC1  A 990 ( 4.8A)
 0.23A 1kxhA-1oseA:
50.9		 1kxhA-1oseA:
47.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
ARG A 195
ASP A 197
LYS A 200
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.71A 1mxdA-1oseA:
28.9		 1mxdA-1oseA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OT7_B_IU5B1002_1
(BILE ACID RECEPTOR)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 LEU A  16
ARG A  72
SER A  73
ILE A 367
ILE A  24
 None
 1.39A 1ot7B-1oseA:
0.0		 1ot7B-1oseA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 372
HIS A 386
 None
 1.14A 2h77A-1oseA:
undetectable		 2h77A-1oseA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWC_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 0.97A 2owcA-1oseA:
13.4		 2owcA-1oseA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OWW_A_ACRA600_1
(4-ALPHA-GLUCANOTRANS
FERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 11 TYR A  62
GLN A  63
ASP A 197
HIS A 299
ASP A 300
TRP A  58
 AC1  A 992 ( 3.6A)
GLC  A 991 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
None
 0.97A 2owwA-1oseA:
13.4		 2owwA-1oseA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 6 PHE A 231
PHE A 229
GLY A  39
GLY A  38
 None
PCA  A   1 ( 4.4A)
None
None
 0.83A 2qr2A-1oseA:
undetectable
2qr2B-1oseA:
undetectable		 2qr2A-1oseA:
18.53
2qr2B-1oseA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B236_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 5 GLY A  39
GLY A  38
PHE A 231
PHE A 229
 None
None
None
PCA  A   1 ( 4.4A)
 0.86A 2qr2A-1oseA:
undetectable
2qr2B-1oseA:
undetectable		 2qr2A-1oseA:
18.53
2qr2B-1oseA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 VAL A 325
TYR A 321
VAL A  14
VAL A 395
 None
 1.21A 2y05A-1oseA:
undetectable
2y05B-1oseA:
undetectable		 2y05A-1oseA:
19.68
2y05B-1oseA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 GLY A 193
LEU A 186
ALA A  97
LEU A 214
LEU A 211
VAL A 210
 None
 1.10A 2yqzB-1oseA:
undetectable		 2yqzB-1oseA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.61A 3aicA-1oseA:
4.8		 3aicA-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.62A 3aicB-1oseA:
4.9		 3aicB-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
TYR A  62
 AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
AC1  A 992 ( 3.6A)
 0.69A 3aicC-1oseA:
4.3		 3aicC-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.66A 3aicD-1oseA:
7.5		 3aicD-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.64A 3aicE-1oseA:
3.0		 3aicE-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.63A 3aicF-1oseA:
10.5		 3aicF-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.60A 3aicG-1oseA:
11.0		 3aicG-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		7 / 12 LEU A 162
ARG A 195
ASP A 197
ALA A 198
GLU A 233
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 (-3.5A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.67A 3aicH-1oseA:
4.3		 3aicH-1oseA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 7 TYR A 342
ILE A 367
GLY A 359
TYR A  62
 None
None
None
AC1  A 992 ( 3.6A)
 0.93A 3elzA-1oseA:
undetectable		 3elzA-1oseA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 7 TYR A  67
LYS A 185
VAL A  95
ILE A 189
 None
 1.19A 3ms9B-1oseA:
undetectable		 3ms9B-1oseA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 6 TYR A 449
VAL A 401
ILE A 427
ARG A 392
 None
 1.11A 3pyyA-1oseA:
undetectable		 3pyyA-1oseA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 6 VAL A  91
VAL A 395
ILE A  13
ARG A  30
 None
 1.10A 3pyyA-1oseA:
undetectable		 3pyyA-1oseA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 GLY A  38
LEU A  16
VAL A  42
TYR A  94
 None
 0.90A 4fgzA-1oseA:
undetectable		 4fgzA-1oseA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_B_CQAB301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 GLY A  38
LEU A  16
VAL A  42
TYR A  94
 None
 0.91A 4fgzB-1oseA:
undetectable		 4fgzB-1oseA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 372
HIS A 386
 None
 1.13A 4lnwA-1oseA:
0.0		 4lnwA-1oseA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ILE A  24
ALA A  25
ARG A  85
ILE A 372
HIS A 386
 None
 1.13A 4lnxA-1oseA:
0.0		 4lnxA-1oseA:
17.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LZR_A_LOCA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 VAL A 210
LEU A 170
ASP A 197
ILE A 196
 None
None
AC1  A 992 ( 3.3A)
None
 0.84A 4lzrA-1oseA:
undetectable		 4lzrA-1oseA:
12.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE0_A_40LA1101_0
(PHOSPHATIDYLINOSITOL
4,5-BISPHOSPHATE
3-KINASE CATALYTIC
SUBUNIT DELTA
ISOFORM)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ILE A 196
VAL A  98
ASP A 167
ASN A 137
ILE A 179
 None
None
CA  A 500 ( 2.2A)
None
None
 1.36A 4xe0A-1oseA:
undetectable		 4xe0A-1oseA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 12 ARG A 195
ASP A 197
GLU A 233
HIS A 299
ASP A 300
 AC1  A 992 ( 3.7A)
AC1  A 992 ( 3.3A)
AC1  A 992 ( 2.7A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.36A 5csyB-1oseA:
5.1		 5csyB-1oseA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 7 PHE A 335
GLY A  36
VAL A 338
ILE A  13
VAL A  14
 None
 1.25A 5ik1A-1oseA:
undetectable		 5ik1A-1oseA:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ACTA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 6 PHE A 429
MET A 394
ILE A 453
ASP A 451
 None
 1.26A 5iwuA-1oseA:
undetectable		 5iwuA-1oseA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 8 VAL A 234
ASP A 236
HIS A 201
GLN A 243
 None
None
AC1  A 992 ( 3.8A)
None
 0.84A 5w3jB-1oseA:
undetectable		 5w3jB-1oseA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
TYR A  62
GLU A 240
TYR A 151
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
BGC  A 993 ( 3.3A)
BGC  A 993 (-4.2A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.30A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.09A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		9 / 12 TRP A  58
TYR A  62
HIS A 101
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.6A)
AC1  A 992 ( 3.7A)
None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.78A 6ag0A-1oseA:
26.7		 6ag0A-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC607_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 6 GLY A  90
GLY A  33
PRO A  34
GLY A  36
 None
 0.72A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 1.01A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
ASP A 300
 None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
AC1  A 992 (-3.0A)
 0.53A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
GLU A 240
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
BGC  A 993 ( 3.3A)
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
 1.10A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_C_ACRC608_0
(ALPHA-AMYLASE)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		6 / 12 TRP A  58
LEU A 162
ASP A 197
LYS A 200
HIS A 201
HIS A 299
 None
None
AC1  A 992 ( 3.3A)
BGC  A 993 ( 2.8A)
AC1  A 992 ( 3.8A)
AC1  A 992 ( 3.9A)
 0.73A 6ag0C-1oseA:
26.7		 6ag0C-1oseA:
8.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 5 PRO A 486
VAL A 323
GLY A 420
VAL A 417
 None
 0.87A 6ak3B-1oseA:
undetectable		 6ak3B-1oseA:
11.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		3 / 3 GLN A 232
TYR A 247
ASN A 250
 None
 1.01A 6dwdC-1oseA:
undetectable		 6dwdC-1oseA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		4 / 5 GLU A 272
VAL A 265
LEU A 277
HIS A 331
 BGC  A 996 (-2.7A)
None
None
None
 1.48A 6dyoA-1oseA:
undetectable		 6dyoA-1oseA:
9.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1ose PORCINE
ALPHA-AMYLASE
(Sus
scrofa) 		5 / 8 GLY A 425
PHE A 426
HIS A 491
GLY A 447
ALA A 475
 None
 1.39A 6hu9H-1oseA:
undetectable
6hu9e-1oseA:
undetectable		 6hu9H-1oseA:
11.09
6hu9e-1oseA:
14.00