SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ou0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E06_B_IPBB600_0
(ODORANT-BINDING
PROTEIN)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 4 ILE A  36
MET A  63
VAL A  80
GLY A 201
 None
 1.40A 1e06B-1ou0A:
undetectable		 1e06B-1ou0A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_A_SAMA270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A 171
GLY A 187
MET A 145
LEU A 175
SER A 184
 None
 1.16A 3gyqA-1ou0A:
undetectable
3gyqB-1ou0A:
undetectable		 3gyqA-1ou0A:
24.14
3gyqB-1ou0A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GYQ_B_SAMB270_0
(RRNA
(ADENOSINE-2'-O-)-ME
THYLTRANSFERASE)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 11 ALA A 171
GLY A 187
MET A 145
LEU A 175
SER A 184
 None
 1.22A 3gyqB-1ou0A:
undetectable		 3gyqB-1ou0A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 10 PRO A 138
SER A 116
ILE A 134
PRO A 162
GLY A 135
 None
 1.24A 3ijxB-1ou0A:
undetectable
3ijxD-1ou0A:
undetectable		 3ijxB-1ou0A:
22.85
3ijxD-1ou0A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 10 PRO A 138
SER A 116
ILE A 134
PRO A 162
GLY A 135
 None
 1.20A 3iluB-1ou0A:
undetectable
3iluE-1ou0A:
undetectable		 3iluB-1ou0A:
22.85
3iluE-1ou0A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 6 TYR A  98
MET A 107
ILE A 122
SER A 130
 None
 1.35A 3pmzD-1ou0A:
0.0		 3pmzD-1ou0A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		4 / 7 ASN A 129
SER A 130
VAL A  96
ARG A  94
 None
 1.13A 4ijiH-1ou0A:
undetectable		 4ijiH-1ou0A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_2
(PROTEASE)		 1ou0 PRECORRIN-8X
METHYLMUTASE RELATED
PROTEIN
(Thermoplasma
acidophilum) 		5 / 12 ALA A  40
GLY A 190
ILE A 198
GLY A 135
ILE A 161
 None
 0.78A 4q5mA-1ou0A:
undetectable		 4q5mA-1ou0A:
23.87