SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_MTLB871_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 8 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.98A 1rs7B-1oulA:
undetectable		 1rs7B-1oulA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YVP_B_ACTB2002_0
(60-KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 6 SER A  55
ALA A  56
SER A  57
THR A  26
 None
 0.75A 1yvpB-1oulA:
undetectable		 1yvpB-1oulA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 8 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 1.03A 1zzuA-1oulA:
0.0		 1zzuA-1oulA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 7 SER A  55
ALA A  56
SER A  57
THR A  26
 None
 0.79A 2i91A-1oulA:
undetectable		 2i91A-1oulA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 7 SER A  55
ALA A  56
SER A  57
THR A  26
 None
 0.79A 2i91B-1oulA:
undetectable		 2i91B-1oulA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_MTLA870_0
(NITRIC OXIDE
SYNTHASE)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 8 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.93A 3n62A-1oulA:
undetectable		 3n62A-1oulA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_MTLB870_0
(NITRIC OXIDE
SYNTHASE)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 8 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.99A 3n62B-1oulA:
undetectable		 3n62B-1oulA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 7 LEU A  52
LEU A  82
PRO A  85
ILE A  84
 None
 0.93A 3s56B-1oulA:
undetectable		 3s56B-1oulA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 7 ASN A  23
TYR A  28
LEU A  54
PHE A  71
 None
 1.07A 4yv5A-1oulA:
undetectable		 4yv5A-1oulA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		5 / 7 VAL A  31
ILE A  50
VAL A  38
PRO A  41
ALA A  33
 None
 1.46A 5ospA-1oulA:
undetectable		 5ospA-1oulA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		5 / 12 PHE A  75
LEU A  52
VAL A  38
ASN A  39
SER A  79
 None
 1.45A 5v1tA-1oulA:
undetectable		 5v1tA-1oulA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_MTLA805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1oul STRINGENT STARVATION
PROTEIN B HOMOLOG
(Haemophilus
influenzae) 		4 / 8 ASN A  72
GLN A  63
PHE A  71
ASN A  39
 None
 0.99A 5vunA-1oulA:
0.0		 5vunA-1oulA:
16.10