SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ouv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SH9_B_RITB301_1
(POL POLYPROTEIN)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		5 / 8 ALA A 163
ASP A 168
ILE A 174
GLY A 141
ILE A 142
 None
 1.20A 1sh9A-1ouvA:
undetectable		 1sh9A-1ouvA:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1503_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		4 / 4 LYS A 234
ARG A 231
ASP A 201
ASP A 197
 None
 1.36A 1zlqA-1ouvA:
0.5		 1zlqA-1ouvA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A  34
ALA A  37
PRO A  29
ALA A  55
TYR A  96
 None
 1.11A 3jayA-1ouvA:
undetectable		 3jayA-1ouvA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		5 / 12 GLY A 135
GLY A 140
GLY A 104
LEU A 121
ILE A 142
 None
 1.19A 3ku1G-1ouvA:
undetectable		 3ku1G-1ouvA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_B_SAMB301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		5 / 12 ALA A 156
ASP A 168
HIS A 101
GLY A 135
TYR A 124
 None
 1.19A 5hfjB-1ouvA:
undetectable		 5hfjB-1ouvA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8D_A_ACTA601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		4 / 4 LYS A 234
ARG A 231
ASP A 201
ASP A 197
 None
 1.38A 5l8dA-1ouvA:
0.1		 5l8dA-1ouvA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWU_A_ACTA601_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		4 / 4 LYS A 234
ARG A 231
ASP A 201
ASP A 197
 None
 1.38A 5mwuA-1ouvA:
0.1		 5mwuA-1ouvA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1ouv CONSERVED
HYPOTHETICAL
SECRETED PROTEIN
(Helicobacter
pylori) 		4 / 4 HIS A 101
LEU A 121
TYR A 143
GLY A 141
 None
 1.50A 6n91B-1ouvA:
0.0		 6n91B-1ouvA:
15.35