SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ovl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		5 / 12 GLU B 445
ALA B 452
PHE B 464
LEU B 470
PHE B 479
 None
None
None
None
K  B 703 ( 4.8A)
 1.16A 1nw3A-1ovlB:
undetectable		 1nw3A-1ovlB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.55A 1v54C-1ovlB:
undetectable
1v54J-1ovlB:
0.0		 1v54C-1ovlB:
19.94
1v54J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.60A 1v54P-1ovlB:
undetectable
1v54W-1ovlB:
0.0		 1v54P-1ovlB:
19.94
1v54W-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.56A 2dyrC-1ovlB:
undetectable
2dyrJ-1ovlB:
0.0		 2dyrC-1ovlB:
19.94
2dyrJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.55A 2dyrP-1ovlB:
undetectable
2dyrW-1ovlB:
0.0		 2dyrP-1ovlB:
19.94
2dyrW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.63A 2eikC-1ovlB:
undetectable
2eikJ-1ovlB:
undetectable		 2eikC-1ovlB:
19.94
2eikJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.61A 2eikP-1ovlB:
undetectable
2eikW-1ovlB:
0.0		 2eikP-1ovlB:
19.94
2eikW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.63A 2eilC-1ovlB:
undetectable
2eilJ-1ovlB:
0.0		 2eilC-1ovlB:
19.94
2eilJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.65A 2eilP-1ovlB:
undetectable
2eilW-1ovlB:
undetectable		 2eilP-1ovlB:
19.94
2eilW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.89A 2eilP-1ovlB:
undetectable
2eilW-1ovlB:
undetectable		 2eilP-1ovlB:
19.94
2eilW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 6 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 1.00A 3abkP-1ovlB:
0.8
3abkW-1ovlB:
0.0		 3abkP-1ovlB:
19.94
3abkW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.64A 3ag2C-1ovlB:
undetectable		 3ag2C-1ovlB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.65A 3ag2P-1ovlB:
undetectable
3ag2W-1ovlB:
undetectable		 3ag2P-1ovlB:
19.94
3ag2W-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.62A 3ag4C-1ovlB:
undetectable
3ag4J-1ovlB:
0.0		 3ag4C-1ovlB:
19.94
3ag4J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.63A 3ag4P-1ovlB:
undetectable
3ag4W-1ovlB:
undetectable		 3ag4P-1ovlB:
19.94
3ag4W-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.60A 3asnC-1ovlB:
0.5
3asnJ-1ovlB:
0.0		 3asnC-1ovlB:
19.94
3asnJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		5 / 8 LEU B 570
GLN B 571
PHE B 574
PHE B 592
LEU B 596
 None
 0.96A 3asoC-1ovlB:
undetectable
3asoJ-1ovlB:
undetectable		 3asoC-1ovlB:
19.94
3asoJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.91A 3asoC-1ovlB:
undetectable
3asoJ-1ovlB:
undetectable		 3asoC-1ovlB:
19.94
3asoJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.28A 3dqtA-1ovlB:
undetectable
3dqtB-1ovlB:
undetectable		 3dqtA-1ovlB:
20.76
3dqtB-1ovlB:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.23A 3n61A-1ovlB:
0.6
3n61B-1ovlB:
0.3		 3n61A-1ovlB:
22.20
3n61B-1ovlB:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 6 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.92A 3wg7C-1ovlB:
undetectable
3wg7J-1ovlB:
undetectable		 3wg7C-1ovlB:
19.94
3wg7J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 6 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.83A 3wg7P-1ovlB:
undetectable
3wg7W-1ovlB:
undetectable		 3wg7P-1ovlB:
19.94
3wg7W-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.63A 3x2qC-1ovlB:
0.7
3x2qJ-1ovlB:
0.0		 3x2qC-1ovlB:
19.94
3x2qJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.63A 3x2qP-1ovlB:
undetectable
3x2qW-1ovlB:
0.0		 3x2qP-1ovlB:
19.94
3x2qW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1475_0
(MJ0495-LIKE PROTEIN)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 8 ILE B 587
ASP B 589
ILE B 588
GLN B 404
 None
 0.83A 4ac9C-1ovlB:
undetectable		 4ac9C-1ovlB:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8Y_C_VK3C202_1
(NADPH QUINONE
OXIDOREDUCTASE)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TYR B 453
LEU B 493
ASN B 497
TYR B 551
 None
 1.17A 4f8yC-1ovlB:
undetectable
4f8yD-1ovlB:
0.2		 4f8yC-1ovlB:
21.03
4f8yD-1ovlB:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 6 VAL B 487
VAL B 448
TRP B 482
PHE B 479
 None
None
None
K  B 703 ( 4.8A)
 0.97A 5addA-1ovlB:
0.5
5addB-1ovlB:
0.2		 5addA-1ovlB:
22.20
5addB-1ovlB:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADL_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.25A 5adlA-1ovlB:
undetectable
5adlB-1ovlB:
1.5		 5adlA-1ovlB:
19.51
5adlB-1ovlB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.72A 5b1aC-1ovlB:
undetectable
5b1aJ-1ovlB:
undetectable		 5b1aC-1ovlB:
19.94
5b1aJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.86A 5b1aC-1ovlB:
undetectable
5b1aJ-1ovlB:
undetectable		 5b1aC-1ovlB:
19.94
5b1aJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.90A 5b1aC-1ovlB:
undetectable
5b1aJ-1ovlB:
undetectable		 5b1aC-1ovlB:
19.94
5b1aJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.68A 5b1aP-1ovlB:
undetectable
5b1aW-1ovlB:
undetectable		 5b1aP-1ovlB:
19.94
5b1aW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.79A 5b1aP-1ovlB:
undetectable
5b1aW-1ovlB:
undetectable		 5b1aP-1ovlB:
19.94
5b1aW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.94A 5b1aP-1ovlB:
undetectable
5b1aW-1ovlB:
undetectable		 5b1aP-1ovlB:
19.94
5b1aW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 6 GLN B 571
PHE B 574
PHE B 592
LEU B 596
 None
 0.81A 5b1bC-1ovlB:
undetectable
5b1bJ-1ovlB:
undetectable		 5b1bC-1ovlB:
19.94
5b1bJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.66A 5b1bP-1ovlB:
0.9
5b1bW-1ovlB:
0.0		 5b1bP-1ovlB:
19.94
5b1bW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.83A 5b1bP-1ovlB:
0.9
5b1bW-1ovlB:
0.0		 5b1bP-1ovlB:
19.94
5b1bW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.71A 5b3sC-1ovlB:
undetectable
5b3sJ-1ovlB:
undetectable		 5b3sC-1ovlB:
19.94
5b3sJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.84A 5b3sC-1ovlB:
undetectable
5b3sJ-1ovlB:
undetectable		 5b3sC-1ovlB:
19.94
5b3sJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.69A 5b3sP-1ovlB:
0.2		 5b3sP-1ovlB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.81A 5b3sP-1ovlB:
0.2		 5b3sP-1ovlB:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ3_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.25A 5fj3A-1ovlB:
undetectable
5fj3B-1ovlB:
undetectable		 5fj3A-1ovlB:
19.51
5fj3B-1ovlB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		5 / 12 LEU B 430
PHE B 427
LEU B 446
ILE B 506
LEU B 559
 None
 1.35A 5ienA-1ovlB:
undetectable		 5ienA-1ovlB:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.73A 5iy5C-1ovlB:
undetectable
5iy5J-1ovlB:
undetectable		 5iy5C-1ovlB:
19.62
5iy5J-1ovlB:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.95A 5iy5C-1ovlB:
undetectable
5iy5J-1ovlB:
undetectable		 5iy5C-1ovlB:
19.62
5iy5J-1ovlB:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 HIS B 471
HIS B 402
VAL B 476
GLN B 394
 None
 1.32A 5kkzM-1ovlB:
undetectable
5kkzO-1ovlB:
undetectable		 5kkzM-1ovlB:
21.82
5kkzO-1ovlB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 5 ARG B 477
THR B 400
HIS B 402
ASP B 398
 None
 1.39A 5mfxA-1ovlB:
undetectable		 5mfxA-1ovlB:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 5 ARG B 563
PHE B 443
LEU B 446
LEU B 570
 None
 1.32A 5veuH-1ovlB:
undetectable		 5veuH-1ovlB:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV7_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.24A 5vv7A-1ovlB:
undetectable
5vv7B-1ovlB:
undetectable		 5vv7A-1ovlB:
19.51
5vv7B-1ovlB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.22A 5vvnA-1ovlB:
undetectable
5vvnB-1ovlB:
undetectable		 5vvnA-1ovlB:
19.51
5vvnB-1ovlB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 5 LEU B 570
PHE B 592
LEU B 596
PHE B 598
 None
 0.95A 5x19C-1ovlB:
undetectable
5x19J-1ovlB:
undetectable		 5x19C-1ovlB:
19.94
5x19J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.67A 5z84C-1ovlB:
undetectable
5z84J-1ovlB:
undetectable		 5z84C-1ovlB:
19.94
5z84J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
PHE B 574
PHE B 592
LEU B 596
 None
 0.87A 5z84C-1ovlB:
undetectable
5z84J-1ovlB:
undetectable		 5z84C-1ovlB:
19.94
5z84J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.69A 5z85C-1ovlB:
undetectable
5z85J-1ovlB:
0.0		 5z85C-1ovlB:
19.94
5z85J-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.67A 5zcoC-1ovlB:
0.4
5zcoJ-1ovlB:
0.0		 5zcoC-1ovlB:
19.94
5zcoJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.68A 5zcqC-1ovlB:
0.4
5zcqJ-1ovlB:
0.0		 5zcqC-1ovlB:
19.94
5zcqJ-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 LEU B 570
GLN B 571
PHE B 574
PHE B 592
 None
 0.69A 5zcqP-1ovlB:
0.6
5zcqW-1ovlB:
0.0		 5zcqP-1ovlB:
19.94
5zcqW-1ovlB:
11.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 SER B 485
VAL B 487
TRP B 482
PHE B 479
 None
None
None
K  B 703 ( 4.8A)
 1.29A 6av6A-1ovlB:
undetectable
6av6B-1ovlB:
undetectable		 6av6A-1ovlB:
13.70
6av6B-1ovlB:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 TRP B 482
PHE B 479
SER B 485
VAL B 487
 None
K  B 703 ( 4.8A)
None
None
 1.25A 6av6C-1ovlB:
undetectable
6av6D-1ovlB:
undetectable		 6av6C-1ovlB:
13.70
6av6D-1ovlB:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		4 / 7 SER B 485
VAL B 487
TRP B 482
PHE B 479
 None
None
None
K  B 703 ( 4.8A)
 1.26A 6av7A-1ovlB:
0.0
6av7B-1ovlB:
undetectable		 6av7A-1ovlB:
13.70
6av7B-1ovlB:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 1ovl ORPHAN NUCLEAR
RECEPTOR NURR1 (MSE
496, 511)
(Homo
sapiens) 		5 / 10 LEU B 409
LEU B 444
PHE B 464
GLY B 569
ARG B 572
 None
 1.02A 6eu9B-1ovlB:
24.0		 6eu9B-1ovlB:
16.47