SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ovm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 7 LEU A 291
THR A 288
GLY A 294
LEU A 542
 None
 0.79A 1gtiB-1ovmA:
0.4		 1gtiB-1ovmA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 1.07A 1hsgB-1ovmA:
undetectable		 1hsgB-1ovmA:
10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 6 ALA A 193
LYS A 196
ASP A 200
ALA A 201
 None
 0.33A 1iwhA-1ovmA:
undetectable		 1iwhA-1ovmA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		3 / 3 ASP A 150
LEU A 153
HIS A  37
 None
 0.62A 1qknA-1ovmA:
undetectable		 1qknA-1ovmA:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 11 ILE A 457
ASN A 461
LEU A 460
ALA A 381
ILE A 489
 None
 1.05A 2aclE-1ovmA:
undetectable		 2aclE-1ovmA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 ALA A 197
PHE A 198
ALA A 202
LEU A 331
 None
 0.56A 2bxmA-1ovmA:
0.0		 2bxmA-1ovmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 10 ALA A 197
PHE A 198
ALA A 202
LEU A 206
LEU A 331
 None
 0.52A 2bxqA-1ovmA:
undetectable		 2bxqA-1ovmA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 9 ILE A 274
GLY A 276
GLU A 272
ALA A 273
THR A 267
 None
 1.15A 2dtjA-1ovmA:
undetectable
2dtjB-1ovmA:
undetectable		 2dtjA-1ovmA:
15.55
2dtjB-1ovmA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 GLY A 104
THR A 105
ALA A 106
ALA A 107
 None
 0.43A 2ej3A-1ovmA:
undetectable		 2ej3A-1ovmA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 GLY A 104
THR A 105
ALA A 106
ALA A 107
 None
 0.42A 2ej3C-1ovmA:
undetectable		 2ej3C-1ovmA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_A_NCAA900_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 ILE A 535
PRO A 536
PHE A 388
ILE A 471
 None
 0.83A 2hjhA-1ovmA:
6.8		 2hjhA-1ovmA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 9 ILE A 402
ALA A  58
CYH A  65
LYS A  66
 None
 1.05A 2vufB-1ovmA:
undetectable		 2vufB-1ovmA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7W_B_SALB1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 10 THR A 433
GLY A 434
GLY A 411
THR A 413
ILE A 410
 None
TPP  A 600 (-3.2A)
None
None
TPP  A 600 (-4.0A)
 1.37A 2y7wB-1ovmA:
undetectable		 2y7wB-1ovmA:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 VAL A 270
PHE A 401
LEU A 395
GLU A 252
SER A 262
 None
 1.40A 3apvB-1ovmA:
0.0		 3apvB-1ovmA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		3 / 3 TRP A  46
VAL A  96
ARG A 222
 None
 0.71A 3b0wA-1ovmA:
0.0		 3b0wA-1ovmA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 9 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 0.96A 3ekvB-1ovmA:
undetectable		 3ekvB-1ovmA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_A_LYAA514_1
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 ALA A 136
LEU A 153
ARG A  14
ILE A  99
LEU A  15
 None
 1.08A 3k2hA-1ovmA:
undetectable		 3k2hA-1ovmA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 6 ILE A 526
VAL A 528
LEU A 460
LEU A 432
 None
 0.67A 3kp6A-1ovmA:
0.0
3kp6B-1ovmA:
undetectable		 3kp6A-1ovmA:
14.75
3kp6B-1ovmA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MS9_B_STIB1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 7 TYR A  10
VAL A  96
VAL A 152
ILE A  99
 None
 1.28A 3ms9B-1ovmA:
undetectable		 3ms9B-1ovmA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 11 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 1.07A 3oxvD-1ovmA:
undetectable		 3oxvD-1ovmA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLY A 376
ASP A 377
ARG A 374
GLN A 254
 None
 1.46A 3qx3A-1ovmA:
2.6		 3qx3A-1ovmA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 453
PHE A 418
TYR A  62
ARG A  64
 None
 1.43A 3sufD-1ovmA:
0.0		 3sufD-1ovmA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 11 LEU A 514
LEU A 458
THR A 371
ILE A 373
LEU A 393
 None
 1.02A 3tqbA-1ovmA:
undetectable		 3tqbA-1ovmA:
14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 10 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 1.09A 4dqcA-1ovmA:
undetectable		 4dqcA-1ovmA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_A_MMZA616_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.37A 4ig5A-1ovmA:
0.0		 4ig5A-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IG5_B_MMZB617_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.35A 4ig5B-1ovmA:
0.0		 4ig5B-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_1
(PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 8 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 1.21A 4ll3A-1ovmA:
undetectable		 4ll3A-1ovmA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 9 ASP A 382
ALA A 437
ASP A 435
VAL A 459
VAL A 431
 None
TPP  A 600 (-3.1A)
MG  A 601 ( 2.9A)
None
None
 1.17A 4ll3B-1ovmA:
undetectable		 4ll3B-1ovmA:
10.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MGH_A_ACTA1320_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 VAL A 283
LEU A 229
ILE A 328
LEU A 331
 None
 0.84A 4mghA-1ovmA:
undetectable		 4mghA-1ovmA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 ALA A 541
GLY A 384
PHE A 388
ASP A 289
THR A 290
 None
TPP  A 600 (-3.5A)
None
None
None
 1.14A 4mm8A-1ovmA:
0.0		 4mm8A-1ovmA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 GLY A 384
PHE A 388
GLY A 540
ASP A 289
THR A 290
 TPP  A 600 (-3.5A)
None
None
None
None
 1.12A 4mm8A-1ovmA:
0.0		 4mm8A-1ovmA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		3 / 3 ALA A 420
GLN A 404
GLY A 408
 None
None
TPP  A 600 (-4.9A)
 0.61A 4odoC-1ovmA:
undetectable		 4odoC-1ovmA:
13.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJ4_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 LEU A 214
LEU A 281
VAL A 283
ILE A 328
 None
 0.85A 4oj4A-1ovmA:
undetectable		 4oj4A-1ovmA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 PRO A 490
LEU A 445
VAL A 431
VAL A 459
 None
 0.94A 4pwdA-1ovmA:
undetectable		 4pwdA-1ovmA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QYN_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 PHE A 401
ILE A 373
ALA A 390
THR A 242
LEU A 221
 None
 1.33A 4qynA-1ovmA:
0.0		 4qynA-1ovmA:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 7 VAL A 459
TRP A 486
ILE A 489
LEU A 440
 None
 1.22A 4xo7B-1ovmA:
undetectable		 4xo7B-1ovmA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA601_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.38A 5ff1A-1ovmA:
0.0		 5ff1A-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_A_MMZA602_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.38A 5ff1A-1ovmA:
0.0		 5ff1A-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB601_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.38A 5ff1B-1ovmA:
undetectable		 5ff1B-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FF1_B_MMZB613_1
(LACTOPEROXIDASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 5 GLN A 337
HIS A 338
GLU A 203
LEU A 334
 None
 1.38A 5ff1B-1ovmA:
undetectable		 5ff1B-1ovmA:
24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 VAL A 517
LEU A 460
LEU A 432
THR A 433
PRO A 455
 None
 1.18A 5hnwB-1ovmA:
undetectable		 5hnwB-1ovmA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 4 GLY A 419
ALA A 415
MET A 448
THR A 441
 None
 1.41A 5n0sB-1ovmA:
0.0		 5n0sB-1ovmA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 ASP A  60
VAL A 403
ALA A 423
VAL A 399
LEU A 221
 None
 1.27A 5tudD-1ovmA:
undetectable		 5tudD-1ovmA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 7 GLY A 446
LEU A 493
ILE A 442
LEU A 414
ILE A 526
 None
 0.79A 5vkqA-1ovmA:
undetectable
5vkqB-1ovmA:
undetectable		 5vkqA-1ovmA:
15.67
5vkqB-1ovmA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 8 GLY A 434
LEU A 542
VAL A 467
ILE A 410
GLY A 411
 TPP  A 600 (-3.2A)
None
TPP  A 600 (-3.4A)
TPP  A 600 (-4.0A)
None
 1.21A 5vkqB-1ovmA:
undetectable
5vkqC-1ovmA:
undetectable		 5vkqB-1ovmA:
15.67
5vkqC-1ovmA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1804_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 8 GLY A 446
LEU A 493
ILE A 442
LEU A 414
ILE A 526
 None
 0.81A 5vkqB-1ovmA:
undetectable
5vkqC-1ovmA:
undetectable		 5vkqB-1ovmA:
15.67
5vkqC-1ovmA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 9 GLY A 446
LEU A 493
ILE A 442
LEU A 414
ILE A 526
 None
 0.78A 5vkqC-1ovmA:
0.0
5vkqD-1ovmA:
0.0		 5vkqC-1ovmA:
15.67
5vkqD-1ovmA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		6 / 12 GLU A 252
GLY A 259
VAL A 283
VAL A 220
GLY A 246
ILE A 249
 None
 1.45A 5vopA-1ovmA:
2.2		 5vopA-1ovmA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W3J_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		4 / 8 ASP A 451
HIS A 454
GLY A 446
LEU A 445
 None
 0.90A 5w3jB-1ovmA:
undetectable		 5w3jB-1ovmA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_B_9KLB402_0
(EST-Y29)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 12 SER A 524
PHE A 372
ILE A 430
LEU A 369
LEU A 510
 None
 1.13A 5zwrB-1ovmA:
undetectable		 5zwrB-1ovmA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1ovm INDOLE-3-PYRUVATE
DECARBOXYLASE
(Enterobacter
cloacae) 		5 / 11 VAL A 429
ALA A 420
TYR A 412
THR A 413
ALA A 417
 None
 1.28A 6dk1C-1ovmA:
0.0		 6dk1C-1ovmA:
18.81