SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ovy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YFB_B_ACTB501_0 (METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER)	1ovy	50S RIBOSOMAL PROTEIN L18 (Geobacillus stearothermophil us)	4 / 6	VAL A 106 ARG A 105 ILE A 71 TYR A 100	None	1.17A	2yfbB-1ovyA: undetectable	2yfbB-1ovyA: 17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_A_MXDA551_1 (PROSTACYCLIN SYNTHASE)	1ovy	50S RIBOSOMAL PROTEIN L18 (Geobacillus stearothermophil us)	4 / 6	ALA A 110 ALA A 74 THR A 68 ASN A 70	None	0.80A	3b6hA-1ovyA: undetectable	3b6hA-1ovyA: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3B6H_B_MXDB551_1 (PROSTACYCLIN SYNTHASE)	1ovy	50S RIBOSOMAL PROTEIN L18 (Geobacillus stearothermophil us)	4 / 6	ALA A 110 ALA A 74 THR A 68 ASN A 70	None	0.84A	3b6hB-1ovyA: undetectable	3b6hB-1ovyA: 12.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_A_ACTA1002_0 (PUTATIVE OXIDOREDUCTASE)	1ovy	50S RIBOSOMAL PROTEIN L18 (Geobacillus stearothermophil us)	4 / 6	ASP A 60 GLY A 78 VAL A 77 THR A 68	None	1.19A	3vqrA-1ovyA: undetectable	3vqrA-1ovyA: 14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_B_ACTB1002_0 (PUTATIVE OXIDOREDUCTASE)	1ovy	50S RIBOSOMAL PROTEIN L18 (Geobacillus stearothermophil us)	4 / 5	ASP A 60 GLY A 78 VAL A 77 THR A 68	None	1.17A	3vqrB-1ovyA: undetectable	3vqrB-1ovyA: 14.61

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YFB_B_ACTB501_0","METHYL-ACCEPTING CHEMOTAXIS TRANSDUCER","1ovy","50S RIBOSOMAL PROTEIN L18","Geobacillus stearothermophilus",4,"VAL A 106;ARG A 105;ILE A  71;TYR A 100","None","1.17A","2yfbB-1ovyA:undetectable","2yfbB-1ovyA:17.83"],["3B6H_A_MXDA551_1","PROSTACYCLIN SYNTHASE","1ovy","50S RIBOSOMAL PROTEIN L18","Geobacillus stearothermophilus",4,"ALA A 110;ALA A  74;THR A  68;ASN A  70","None","0.80A","3b6hA-1ovyA:undetectable","3b6hA-1ovyA:12.50"],["3B6H_B_MXDB551_1","PROSTACYCLIN SYNTHASE","1ovy","50S RIBOSOMAL PROTEIN L18","Geobacillus stearothermophilus",4,"ALA A 110;ALA A  74;THR A  68;ASN A  70","None","0.84A","3b6hB-1ovyA:undetectable","3b6hB-1ovyA:12.50"],["3VQR_A_ACTA1002_0","PUTATIVE OXIDOREDUCTASE","1ovy","50S RIBOSOMAL PROTEIN L18","Geobacillus stearothermophilus",4,"ASP A  60;GLY A  78;VAL A  77;THR A  68","None","1.19A","3vqrA-1ovyA:undetectable","3vqrA-1ovyA:14.61"],["3VQR_B_ACTB1002_0","PUTATIVE OXIDOREDUCTASE","1ovy","50S RIBOSOMAL PROTEIN L18","Geobacillus stearothermophilus",4,"ASP A  60;GLY A  78;VAL A  77;THR A  68","None","1.17A","3vqrB-1ovyA:undetectable","3vqrB-1ovyA:14.61"]]