SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ow1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1ow1 SMART/HDAC1
ASSOCIATED REPRESSOR
PROTEIN
(Homo
sapiens) 		5 / 10 LEU A3595
SER A3594
LEU A3515
PHE A3629
ILE A3628
 None
 1.23A 1g5yC-1ow1A:
undetectable		 1g5yC-1ow1A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 1ow1 SMART/HDAC1
ASSOCIATED REPRESSOR
PROTEIN
(Homo
sapiens) 		4 / 6 ILE A3600
HIS A3656
PRO A3580
LEU A3595
 None
 0.97A 3oi8A-1ow1A:
undetectable		 3oi8A-1ow1A:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 1ow1 SMART/HDAC1
ASSOCIATED REPRESSOR
PROTEIN
(Homo
sapiens) 		5 / 7 ILE A3650
LEU A3646
LEU A3575
HIS A3656
VAL A3563
 None
 1.44A 3r9vA-1ow1A:
undetectable
3r9vB-1ow1A:
undetectable		 3r9vA-1ow1A:
21.59
3r9vB-1ow1A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IM2_A_BEZA401_0
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL)		 1ow1 SMART/HDAC1
ASSOCIATED REPRESSOR
PROTEIN
(Homo
sapiens) 		5 / 12 PHE A3599
PRO A3546
LEU A3513
VAL A3522
GLN A3591
 None
 1.10A 5im2A-1ow1A:
undetectable		 5im2A-1ow1A:
18.59