SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ox8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGR_A_T27A556_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H
P51 RT)		 1ox8 STRINGENT STARVATION
PROTEIN B
(Escherichia
coli) 		5 / 11 LEU A  65
VAL A  90
PHE A  72
LEU A  63
TYR A  18
 None
 1.49A 3bgrA-1ox8A:
undetectable
3bgrB-1ox8A:
undetectable		 3bgrA-1ox8A:
12.90
3bgrB-1ox8A:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYM_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1ox8 STRINGENT STARVATION
PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A  65
VAL A  90
PHE A  72
LEU A  63
TYR A  18
 None
 1.44A 5cymA-1ox8A:
undetectable		 5cymA-1ox8A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CYQ_A_T27A601_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1ox8 STRINGENT STARVATION
PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A  65
VAL A  90
PHE A  72
LEU A  63
TYR A  18
 None
 1.43A 5cyqA-1ox8A:
undetectable		 5cyqA-1ox8A:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E5Z_A_CCSA106_0
(PROTEIN/NUCLEIC ACID
DEGLYCASE DJ-1)		 1ox8 STRINGENT STARVATION
PROTEIN B
(Escherichia
coli) 		5 / 10 GLY A  99
ASN A  98
ILE A  93
ALA A  95
PRO A  28
 None
 1.05A 6e5zA-1ox8A:
undetectable		 6e5zA-1ox8A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ELI_A_T27A701_1
(REVERSE
TRANSCRIPTASE)		 1ox8 STRINGENT STARVATION
PROTEIN B
(Escherichia
coli) 		5 / 12 LEU A  65
VAL A  90
PHE A  72
LEU A  63
TYR A  18
 None
 1.43A 6eliA-1ox8A:
undetectable		 6eliA-1ox8A:
17.59