SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oy1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQH_B_FLPB1701_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		6 / 12 VAL A 116
VAL A  94
ILE A 139
GLY A  99
ALA A 100
SER A  12
 None
 1.23A 1eqhB-1oy1A:
0.7		 1eqhB-1oy1A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IGX_A_EPAA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 8 VAL A 116
VAL A   9
VAL A  94
ILE A 139
LEU A 104
 None
 1.27A 1igxA-1oy1A:
undetectable		 1igxA-1oy1A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 11 ILE A  68
LEU A  67
GLY A  13
SER A  12
LEU A 104
 None
 1.34A 1kyvA-1oy1A:
4.5
1kyvB-1oy1A:
3.5		 1kyvA-1oy1A:
20.26
1kyvB-1oy1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		3 / 3 ILE A 208
LEU A 211
VAL A 215
 None
 0.34A 1mz9B-1oy1A:
undetectable		 1mz9B-1oy1A:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 9 LEU A 154
ALA A 142
LEU A 144
GLU A 168
ALA A 171
 None
 1.47A 1sn0A-1oy1A:
undetectable
1sn0C-1oy1A:
0.0		 1sn0A-1oy1A:
19.30
1sn0C-1oy1A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ALA A 204
THR A 192
ILE A 208
GLY A 157
ALA A 198
 None
 0.97A 1utdL-1oy1A:
undetectable
1utdM-1oy1A:
undetectable		 1utdL-1oy1A:
16.00
1utdM-1oy1A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ALA A 204
THR A 192
ILE A 208
GLY A 157
ALA A 198
 None
 0.95A 1utdO-1oy1A:
undetectable
1utdP-1oy1A:
undetectable		 1utdO-1oy1A:
16.00
1utdP-1oy1A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_P_TRPP81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 11 ALA A 204
THR A 192
ILE A 208
GLY A 157
ALA A 198
 None
 0.96A 1utdP-1oy1A:
undetectable
1utdQ-1oy1A:
undetectable		 1utdP-1oy1A:
16.00
1utdQ-1oy1A:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_B_RBFB301_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  68
LEU A  67
GLY A  13
SER A  12
LEU A 104
 None
 1.31A 2a58A-1oy1A:
4.3
2a58B-1oy1A:
4.3		 2a58A-1oy1A:
20.26
2a58B-1oy1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_C_RBFC302_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  68
LEU A  67
GLY A  13
SER A  12
LEU A 104
 None
 1.31A 2a58B-1oy1A:
4.3
2a58C-1oy1A:
4.1		 2a58B-1oy1A:
20.26
2a58C-1oy1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A58_E_RBFE304_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  68
LEU A  67
GLY A  13
SER A  12
LEU A 104
 None
 1.31A 2a58D-1oy1A:
4.1
2a58E-1oy1A:
4.4		 2a58D-1oy1A:
20.26
2a58E-1oy1A:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 11 GLY A  97
SER A  20
SER A  12
ALA A 124
ILE A  93
 None
 0.95A 2nnhA-1oy1A:
undetectable		 2nnhA-1oy1A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QK8_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ALA A 126
ILE A 189
LEU A 144
PRO A 141
PHE A 148
 None
 1.08A 2qk8A-1oy1A:
undetectable		 2qk8A-1oy1A:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_A_J3ZA2_1
(ESTROGEN RECEPTOR)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 LEU A  27
THR A  28
ALA A  31
LEU A 211
MET A 137
 None
 0.78A 3hm1A-1oy1A:
undetectable		 3hm1A-1oy1A:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_A_SAMA401_0
(METHYLTRANSFERASE
MPPJ)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 GLY A  13
GLY A  15
ARG A  64
ALA A  25
ALA A  43
 None
 1.09A 4kicA-1oy1A:
3.6		 4kicA-1oy1A:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 GLU A  21
CYH A 138
MET A 196
ALA A 205
GLY A 207
 None
 1.21A 4oadA-1oy1A:
undetectable		 4oadA-1oy1A:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		4 / 8 PHE A  42
ALA A  86
LEU A  89
GLY A   8
 None
 0.99A 4xk8a-1oy1A:
undetectable		 4xk8a-1oy1A:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  73
SER A  20
GLY A  13
ALA A  70
THR A  74
 None
 1.22A 4xt8A-1oy1A:
undetectable		 4xt8A-1oy1A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 11 MET A 127
LEU A 123
LEU A 120
LEU A  29
LEU A  89
 None
 1.01A 4zowA-1oy1A:
0.1		 4zowA-1oy1A:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 9 THR A  28
VAL A   9
GLY A   8
VAL A 215
VAL A 212
 None
 1.41A 5cp4A-1oy1A:
0.0		 5cp4A-1oy1A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_0
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		6 / 12 ALA A 100
GLY A  96
MET A 137
GLY A  19
SER A  12
LEU A  81
 None
 1.13A 5gwxA-1oy1A:
3.9		 5gwxA-1oy1A:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		3 / 3 LYS A 188
ASP A 186
ILE A 181
 None
 0.84A 5kc4E-1oy1A:
undetectable		 5kc4E-1oy1A:
25.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  22
SER A  12
ASP A  18
GLY A  13
HIS A  54
 None
 1.04A 5nnaA-1oy1A:
undetectable		 5nnaA-1oy1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  22
SER A  12
ASP A  18
GLY A  13
HIS A  54
 None
 1.04A 5nnaB-1oy1A:
undetectable		 5nnaB-1oy1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  22
SER A  12
ASP A  18
GLY A  13
HIS A  54
 None
 1.04A 5nnaC-1oy1A:
undetectable		 5nnaC-1oy1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 12 ILE A  22
SER A  12
ASP A  18
GLY A  13
HIS A  54
 None
 1.06A 5nnaD-1oy1A:
undetectable		 5nnaD-1oy1A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_1_PQN1842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		5 / 10 PHE A 150
ARG A 153
LEU A 152
ILE A  10
LEU A  81
 None
 1.06A 5oy01-1oy1A:
undetectable
5oy07-1oy1A:
undetectable		 5oy01-1oy1A:
16.00
5oy07-1oy1A:
10.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		4 / 7 LEU A 144
ALA A 140
ILE A 156
LEU A 166
 None
 0.84A 5te8C-1oy1A:
undetectable		 5te8C-1oy1A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_C_08JC602_1
(CYTOCHROME P450 3A4)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		4 / 7 SER A 105
THR A 162
ILE A 156
LEU A 166
 None
 0.96A 5te8C-1oy1A:
undetectable		 5te8C-1oy1A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1oy1 PUTATIVE SIGMA
CROSS-REACTING
PROTEIN 27A
(Escherichia
coli) 		3 / 3 LEU A 218
GLY A 131
PHE A 148
 None
 0.67A 6exiC-1oy1A:
4.5		 6exiC-1oy1A:
17.14