SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ABL_C_CHDC271_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1 CYTOCHROME C OXIDASE SUBUNIT 3)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	4 / 5	GLN A 19 PHE A 17 LEU A 73 PHE A 164	None GSH A 799 (-4.0A) None None	1.47A	3ablC-1oyjA: 2.5 3ablJ-1oyjA: 0.0	3ablC-1oyjA: 19.29 3ablJ-1oyjA: 18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q1E_D_T44D328_1 (5-HYDROXYISOURATE HYDROLASE)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	5 / 9	LEU A 9 PRO A 57 LEU A 59 HIS A 210 LEU A 73	None GSH A 799 (-4.2A) None None None	1.42A	3q1eB-1oyjA: 0.0 3q1eD-1oyjA: 0.0	3q1eB-1oyjA: 18.45 3q1eD-1oyjA: 18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VLN_A_ASCA904_0 (GLUTATHIONE S-TRANSFERASE OMEGA-1)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	5 / 6	PHE A 17 ARG A 20 PRO A 57 GLU A 68 SER A 69	GSH A 799 (-4.0A) None GSH A 799 (-4.2A) GSH A 799 (-2.7A) GSH A 799 (-2.6A)	0.37A	3vlnA-1oyjA: 23.3	3vlnA-1oyjA: 25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4W5T_A_IPHA902_0 (PROTEIN ARGONAUTE-2)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	4 / 6	ARG A 20 CYH A 21 ILE A 23 GLN A 19	None	1.21A	4w5tA-1oyjA: 0.0	4w5tA-1oyjA: 12.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z2E_F_TR6F101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B SYMMETRIZED E-SITE DNA)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	4 / 5	GLY A 119 ARG A 121 GLY A 134 GLU A 136	None GSH A 800 (-3.6A) None GSH A 800 (-3.6A)	1.15A	4z2eB-1oyjA: undetectable 4z2eC-1oyjA: undetectable	4z2eB-1oyjA: 16.63 4z2eC-1oyjA: 20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNZ_B_TA1B902_2 (TUBULIN BETA-2B CHAIN)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	3 / 3	LEU A 115 LEU A 144 ARG A 105	None	0.62A	5hnzB-1oyjA: undetectable	5hnzB-1oyjA: 20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LJB_A_RTLA201_0 (RETINOL-BINDING PROTEIN 1)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	5 / 12	SER A 15 PHE A 17 ARG A 20 MET A 25 ILE A 72	GSH A 799 (-3.3A) GSH A 799 (-4.0A) None None None	1.29A	5ljbA-1oyjA: undetectable	5ljbA-1oyjA: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X24_A_LSNA503_1 (CYTOCHROME P450 2C9)	1oyj	GLUTATHIONE S-TRANSFERASE (Oryza sativa)	4 / 6	PHE A 80 PRO A 81 GLY A 82 THR A 83	None CL A 823 ( 4.1A) CL A 823 (-3.5A) CL A 823 ( 4.7A)	0.41A	5x24A-1oyjA: undetectable	5x24A-1oyjA: 19.77

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ABL_C_CHDC271_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1;CYTOCHROME C OXIDASE SUBUNIT 3","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",4,"GLN A  19;PHE A  17;LEU A  73;PHE A 164","None;GSH A 799 (-4.0A);None;None","1.47A","3ablC-1oyjA:2.5;3ablJ-1oyjA:0.0","3ablC-1oyjA:19.29;3ablJ-1oyjA:18.57"],["3Q1E_D_T44D328_1","5-HYDROXYISOURATE HYDROLASE;5-HYDROXYISOURATE HYDROLASE","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",5,"LEU A   9;PRO A  57;LEU A  59;HIS A 210;LEU A  73","None;GSH A 799 (-4.2A);None;None;None","1.42A","3q1eB-1oyjA:0.0;3q1eD-1oyjA:0.0","3q1eB-1oyjA:18.45;3q1eD-1oyjA:18.45"],["3VLN_A_ASCA904_0","GLUTATHIONE S-TRANSFERASE OMEGA-1","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",5,"PHE A  17;ARG A  20;PRO A  57;GLU A  68;SER A  69","GSH A 799 (-4.0A);None;GSH A 799 (-4.2A);GSH A 799 (-2.7A);GSH A 799 (-2.6A)","0.37A","3vlnA-1oyjA:23.3","3vlnA-1oyjA:25.10"],["4W5T_A_IPHA902_0","PROTEIN ARGONAUTE-2","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",4,"ARG A  20;CYH A  21;ILE A  23;GLN A  19","None","1.21A","4w5tA-1oyjA:0.0","4w5tA-1oyjA:12.68"],["4Z2E_F_TR6F101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;SYMMETRIZED E-SITE DNA","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",4,"GLY A 119;ARG A 121;GLY A 134;GLU A 136","None;GSH A 800 (-3.6A);None;GSH A 800 (-3.6A)","1.15A","4z2eB-1oyjA:undetectable;4z2eC-1oyjA:undetectable","4z2eB-1oyjA:16.63;4z2eC-1oyjA:20.80"],["5HNZ_B_TA1B902_2","TUBULIN BETA-2B CHAIN","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",3,"LEU A 115;LEU A 144;ARG A 105","None","0.62A","5hnzB-1oyjA:undetectable","5hnzB-1oyjA:20.33"],["5LJB_A_RTLA201_0","RETINOL-BINDING PROTEIN 1","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",5,"SER A  15;PHE A  17;ARG A  20;MET A  25;ILE A  72","GSH A 799 (-3.3A);GSH A 799 (-4.0A);None;None;None","1.29A","5ljbA-1oyjA:undetectable","5ljbA-1oyjA:21.65"],["5X24_A_LSNA503_1","CYTOCHROME P450 2C9","1oyj","GLUTATHIONE S-TRANSFERASE","Oryza sativa",4,"PHE A  80;PRO A  81;GLY A  82;THR A  83","None; CL A 823 ( 4.1A); CL A 823 (-3.5A); CL A 823 ( 4.7A)","0.41A","5x24A-1oyjA:undetectable","5x24A-1oyjA:19.77"]]