SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oyz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A7Q_A_CFBA328_2
(DEOXYCYTIDINE KINASE)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 4 ILE A 112
ASP A 170
LEU A 163
ARG A 108
 None
 1.16A 2a7qA-1oyzA:
undetectable		 2a7qA-1oyzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		5 / 12 GLY A  52
ARG A  50
ASP A  54
ALA A  55
ALA A  59
 None
 1.19A 2br4B-1oyzA:
undetectable		 2br4B-1oyzA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 7 GLY A  74
SER A 114
PHE A  76
GLU A 113
 None
 1.02A 2c8aB-1oyzA:
undetectable		 2c8aB-1oyzA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 7 GLY A  74
SER A 114
PHE A  76
GLU A 113
 None
 1.03A 2c8aD-1oyzA:
undetectable		 2c8aD-1oyzA:
23.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 7 ASP A  26
ARG A  57
LEU A  58
GLU A  61
 None
 1.02A 2cdqB-1oyzA:
0.0		 2cdqB-1oyzA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA802_1
(TRANSPORTER)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 7 ILE A 214
ARG A 194
PHE A 197
ILE A 193
 None
 0.75A 2qb4A-1oyzA:
0.0		 2qb4A-1oyzA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		3 / 3 LYS A 121
ILE A  60
PHE A  62
 None
 0.89A 3j7zS-1oyzA:
0.0
3j7za-1oyzA:
undetectable		 3j7zS-1oyzA:
18.57
3j7za-1oyzA:
6.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		5 / 12 MET A 260
LEU A 257
LEU A 254
ILE A 242
ILE A 241
 None
 1.22A 4j24B-1oyzA:
undetectable		 4j24B-1oyzA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKN_B_KANB403_1
(L-LACTATE
DEHYDROGENASE A
CHAIN)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		5 / 9 ALA A  44
ARG A 118
ILE A  77
PHE A  62
ILE A  73
 None
 1.40A 4oknB-1oyzA:
undetectable		 4oknB-1oyzA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA602_1
(SERUM ALBUMIN)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 8 ALA A 245
GLY A 249
LEU A 277
LEU A 257
 None
 0.89A 4po0A-1oyzA:
2.5		 4po0A-1oyzA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 1oyz HYPOTHETICAL PROTEIN
YIBA
(Escherichia
coli) 		4 / 6 ARG A 145
SER A 141
ALA A 109
ALA A 149
 None
 1.16A 6ma6A-1oyzA:
0.0		 6ma6A-1oyzA:
13.21