SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1oz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		3 / 3 HIS A 115
HIS A 119
HIS A 125
 None
 0.38A 2ozrF-1oz9A:
6.3		 2ozrF-1oz9A:
24.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		3 / 3 ARG A  10
SER A  44
TYR A  81
 None
 1.00A 2q2hA-1oz9A:
undetectable
2q2hB-1oz9A:
undetectable		 2q2hA-1oz9A:
17.95
2q2hB-1oz9A:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_A_486A1000_2
(PROGESTERONE
RECEPTOR)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 7 LEU A  38
ASN A   9
GLU A  30
LEU A  31
 None
 1.25A 2w8yA-1oz9A:
0.0		 2w8yA-1oz9A:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_B_ACTB1463_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 7 VAL A  13
ILE A  25
ALA A  29
VAL A  11
 None
 0.72A 2xrzB-1oz9A:
undetectable		 2xrzB-1oz9A:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 6 ASP A  23
ILE A  25
LEU A  15
GLU A 106
 None
 1.02A 2ya7A-1oz9A:
undetectable		 2ya7A-1oz9A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 6 ASP A  23
ILE A  25
LEU A  15
GLU A 106
 None
 1.07A 2ya7B-1oz9A:
undetectable		 2ya7B-1oz9A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 6 ASP A  23
ILE A  25
LEU A  15
GLU A 106
 None
 1.07A 2ya7D-1oz9A:
undetectable		 2ya7D-1oz9A:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 5 GLU A  77
GLY A  75
TYR A  81
GLU A  42
 None
 1.37A 3w9tA-1oz9A:
undetectable		 3w9tA-1oz9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 5 GLU A  77
GLY A  75
TYR A  81
GLU A  42
 None
 1.38A 3w9tC-1oz9A:
undetectable		 3w9tC-1oz9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 5 GLU A  77
GLY A  75
TYR A  81
GLU A  42
 None
 1.38A 3w9tD-1oz9A:
undetectable		 3w9tD-1oz9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 5 GLU A  77
GLY A  75
TYR A  81
GLU A  42
 None
 1.38A 3w9tG-1oz9A:
undetectable		 3w9tG-1oz9A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQA_B_ID8B401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		5 / 9 VAL A 142
TYR A 141
VAL A 114
ILE A 117
LEU A  38
 None
 1.20A 4jqaB-1oz9A:
0.0		 4jqaB-1oz9A:
24.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 7 GLN A  97
THR A  93
ILE A  53
ASP A  50
 None
 1.01A 4pcuA-1oz9A:
undetectable		 4pcuA-1oz9A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_B_010B607_0
(HNL ISOENZYME 5)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		5 / 10 ALA A  32
ALA A  29
VAL A  45
LEU A 121
VAL A  87
 None
 1.12A 5eb5B-1oz9A:
undetectable		 5eb5B-1oz9A:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 9 ILE A  47
ILE A 113
ILE A 117
LEU A 120
 None
 0.78A 5vkqB-1oz9A:
undetectable
5vkqC-1oz9A:
undetectable		 5vkqB-1oz9A:
6.67
5vkqC-1oz9A:
6.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_A_GMJA301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 6 SER A  71
ASP A 124
GLU A 126
THR A  67
 None
 1.38A 6djzA-1oz9A:
0.0		 6djzA-1oz9A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 5 VAL A  69
LEU A 112
HIS A 103
THR A  93
 None
 1.49A 6dyoA-1oz9A:
undetectable		 6dyoA-1oz9A:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUO_D_08HD501_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT GAMMA-2)		 1oz9 HYPOTHETICAL PROTEIN
AQ_1354
(Aquifex
aeolicus) 		4 / 8 PHE A 135
HIS A 115
VAL A  69
SER A  71
 None
 0.89A 6huoC-1oz9A:
undetectable
6huoD-1oz9A:
0.0		 6huoC-1oz9A:
23.97
6huoD-1oz9A:
22.67