SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p0n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 LEU A 242
THR A  23
ASP A 207
LEU A 260
GLY A 258
 None
None
None
None
FMN  A 669 (-3.0A)
 1.20A 1d4fA-1p0nA:
undetectable		 1d4fA-1p0nA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_D_ADND604_1
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 LEU A 242
THR A  23
ASP A 207
LEU A 260
GLY A 258
 None
None
None
None
FMN  A 669 (-3.0A)
 1.20A 1d4fD-1p0nA:
0.0		 1d4fD-1p0nA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 11 LEU A  98
ALA A 141
ALA A 135
MET A 138
TYR A 107
 None
 1.41A 1iiuA-1p0nA:
undetectable		 1iiuA-1p0nA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KGL_A_RTLA175_1
(CELLULAR
RETINOL-BINDING
PROTEIN TYPE I)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 7 LEU A 272
ILE A  58
THR A 277
MET A 279
 None
 1.28A 1kglA-1p0nA:
0.0		 1kglA-1p0nA:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 5 GLU A 298
THR A 288
LEU A 284
LEU A 287
 None
 1.18A 1u18B-1p0nA:
undetectable		 1u18B-1p0nA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_B_URFB999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 7 MET A 254
ALA A 256
ILE A 208
ILE A 245
 None
 0.91A 1upfB-1p0nA:
undetectable		 1upfB-1p0nA:
24.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 SER A 257
ALA A 141
ILE A 139
ILE A 119
ALA A  90
 None
 1.06A 2bxcA-1p0nA:
undetectable		 2bxcA-1p0nA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_B_ADNB2005_1
(TRYPTOPHAN
HALOGENASE)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 7 GLY A 258
GLY A 259
VAL A 186
SER A 257
 FMN  A 669 (-3.0A)
FMN  A 669 (-4.2A)
None
None
 0.80A 2oa1B-1p0nA:
undetectable		 2oa1B-1p0nA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 ALA A 256
SER A 237
GLY A 210
GLY A 209
ALA A 243
 None
 0.86A 3douA-1p0nA:
undetectable		 3douA-1p0nA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 VAL A 183
LEU A 148
ALA A 132
GLY A 202
ALA A 201
 None
 1.00A 3ln1A-1p0nA:
undetectable		 3ln1A-1p0nA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 VAL A 183
LEU A 148
ALA A 132
GLY A 202
ALA A 201
 None
 1.02A 3ln1B-1p0nA:
undetectable		 3ln1B-1p0nA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 VAL A 183
LEU A 148
ALA A 132
GLY A 202
ALA A 201
 None
 1.00A 3ln1C-1p0nA:
undetectable		 3ln1C-1p0nA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 VAL A 183
LEU A 148
ALA A 132
GLY A 202
ALA A 201
 None
 1.02A 3ln1D-1p0nA:
undetectable		 3ln1D-1p0nA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 LEU A 295
THR A  71
ILE A  74
SER A  77
ILE A 299
 None
 1.24A 3vw1D-1p0nA:
0.5		 3vw1D-1p0nA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 8 GLY A  50
LEU A  52
ILE A 182
THR A 253
 None
 0.85A 4em2A-1p0nA:
undetectable		 4em2A-1p0nA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 6 SER A 247
GLU A 248
GLY A  24
ASP A  27
 None
 0.85A 5cdnC-1p0nA:
undetectable
5cdnD-1p0nA:
undetectable		 5cdnC-1p0nA:
22.55
5cdnD-1p0nA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 6 SER A 247
GLU A 248
GLY A  24
ASP A  27
 None
 0.85A 5cdnT-1p0nA:
undetectable
5cdnU-1p0nA:
undetectable		 5cdnT-1p0nA:
22.55
5cdnU-1p0nA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H2U_A_1N1A501_2
(PROTEIN-TYROSINE
KINASE 6)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		3 / 3 ILE A  28
MET A 310
ASP A 265
 None
 0.83A 5h2uA-1p0nA:
undetectable		 5h2uA-1p0nA:
23.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MLM_A_STRA401_1
(-)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 MET A 310
PHE A  30
ILE A 309
SER A  56
VAL A 266
 None
 1.48A 5mlmA-1p0nA:
2.1		 5mlmA-1p0nA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB307_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		3 / 3 LEU A 287
ALA A 286
LEU A  78
 None
 0.44A 5uunB-1p0nA:
undetectable		 5uunB-1p0nA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZWR_A_9KLA402_0
(EST-Y29)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		5 / 12 PHE A 283
ILE A 302
GLY A  86
ALA A  85
LEU A 296
 None
 1.06A 5zwrA-1p0nA:
undetectable		 5zwrA-1p0nA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1p0n ISOPENTENYL-DIPHOSPH
ATE DELTA-ISOMERASE
(Bacillus
subtilis) 		4 / 5 LEU A 242
THR A 238
THR A 332
GLY A  24
 None
 1.11A 6gtqA-1p0nA:
0.0		 6gtqA-1p0nA:
18.47