SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p16'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 6 TYR A 117
GLU A 113
ILE A 102
GLY A  86
None
1.13A 1maaB-1p16A:
undetectable
1maaD-1p16A:
undetectable
1maaB-1p16A:
23.72
1maaD-1p16A:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
3 / 3 ASP A 206
LYS A 376
ARG A 379
None
0.71A 1ra8A-1p16A:
undetectable
1ra8A-1p16A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.06A 1v55C-1p16A:
undetectable
1v55N-1p16A:
undetectable
1v55P-1p16A:
undetectable
1v55C-1p16A:
20.60
1v55N-1p16A:
20.40
1v55P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 6 LEU A 239
LEU A 147
MET A 199
LEU A 159
G  A1167 (-4.5A)
None
None
None
1.00A 1z95A-1p16A:
undetectable
1z95A-1p16A:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 ARG A  72
ASP A 145
ASP A 124
TYR A 231
G  A1167 ( 4.7A)
None
None
None
1.06A 2e5dA-1p16A:
undetectable
2e5dB-1p16A:
undetectable
2e5dA-1p16A:
22.29
2e5dB-1p16A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 ASP A 124
TYR A 231
ARG A  72
ASP A 145
None
None
G  A1167 ( 4.7A)
None
1.06A 2e5dA-1p16A:
undetectable
2e5dB-1p16A:
undetectable
2e5dA-1p16A:
22.29
2e5dB-1p16A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.13A 2y69C-1p16A:
undetectable
2y69N-1p16A:
undetectable
2y69P-1p16A:
undetectable
2y69C-1p16A:
20.60
2y69N-1p16A:
20.40
2y69P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.09A 3ablA-1p16A:
undetectable
3ablC-1p16A:
undetectable
3ablP-1p16A:
undetectable
3ablA-1p16A:
20.40
3ablC-1p16A:
20.60
3ablP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.10A 3ablC-1p16A:
undetectable
3ablN-1p16A:
undetectable
3ablP-1p16A:
undetectable
3ablC-1p16A:
20.60
3ablN-1p16A:
20.40
3ablP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.13A 3abmA-1p16A:
undetectable
3abmC-1p16A:
undetectable
3abmP-1p16A:
undetectable
3abmA-1p16A:
20.40
3abmC-1p16A:
20.60
3abmP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.06A 3asnC-1p16A:
undetectable
3asnN-1p16A:
undetectable
3asnP-1p16A:
undetectable
3asnC-1p16A:
20.60
3asnN-1p16A:
20.40
3asnP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.08A 3asoA-1p16A:
undetectable
3asoC-1p16A:
undetectable
3asoP-1p16A:
undetectable
3asoA-1p16A:
20.40
3asoC-1p16A:
20.60
3asoP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.08A 3asoC-1p16A:
undetectable
3asoN-1p16A:
undetectable
3asoP-1p16A:
undetectable
3asoC-1p16A:
20.60
3asoN-1p16A:
20.40
3asoP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D9L_A_ACTA501_0
(CTD-PEPTIDE
RNA-BINDING PROTEIN
16)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 5 PRO A 100
ILE A  99
PRO A  13
TYR A  97
None
1.24A 3d9lA-1p16A:
undetectable
3d9lY-1p16A:
undetectable
3d9lA-1p16A:
14.43
3d9lY-1p16A:
4.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 5 PHE A 256
PHE A 341
ALA A 324
LEU A 304
None
1.10A 3t3zC-1p16A:
undetectable
3t3zC-1p16A:
23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.20A 3wg7A-1p16A:
undetectable
3wg7C-1p16A:
undetectable
3wg7P-1p16A:
undetectable
3wg7A-1p16A:
20.40
3wg7C-1p16A:
20.60
3wg7P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.16A 3wg7C-1p16A:
undetectable
3wg7N-1p16A:
undetectable
3wg7P-1p16A:
undetectable
3wg7C-1p16A:
20.60
3wg7N-1p16A:
20.40
3wg7P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.13A 3x2qA-1p16A:
undetectable
3x2qC-1p16A:
undetectable
3x2qP-1p16A:
undetectable
3x2qA-1p16A:
20.40
3x2qC-1p16A:
20.60
3x2qP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.09A 3x2qC-1p16A:
undetectable
3x2qN-1p16A:
undetectable
3x2qP-1p16A:
undetectable
3x2qC-1p16A:
20.60
3x2qN-1p16A:
20.40
3x2qP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 6 PRO A  13
GLY A  14
ASN A  15
ASN A 101
None
1.01A 3zqtA-1p16A:
undetectable
3zqtA-1p16A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KF9_A_ACTA408_0
(GLUTATHIONE
S-TRANSFERASE
PROTEIN)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 6 TYR A 231
PRO A  41
PHE A 144
PHE A  40
None
None
G  A1167 (-3.7A)
None
1.37A 4kf9A-1p16A:
0.0
4kf9A-1p16A:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
3 / 3 ASP A 213
TRP A 242
SER A 219
None
1.04A 4lrhF-1p16A:
undetectable
4lrhF-1p16A:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A 239
LEU A 147
MET A 199
LEU A 159
G  A1167 (-4.5A)
None
None
None
1.01A 4okwA-1p16A:
undetectable
4okwA-1p16A:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.18A 5b1aA-1p16A:
undetectable
5b1aC-1p16A:
undetectable
5b1aP-1p16A:
undetectable
5b1aA-1p16A:
20.40
5b1aC-1p16A:
20.60
5b1aP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.04A 5b1bA-1p16A:
undetectable
5b1bC-1p16A:
undetectable
5b1bP-1p16A:
undetectable
5b1bA-1p16A:
20.40
5b1bC-1p16A:
20.60
5b1bP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.15A 5b3sA-1p16A:
undetectable
5b3sC-1p16A:
undetectable
5b3sP-1p16A:
undetectable
5b3sA-1p16A:
20.40
5b3sC-1p16A:
20.60
5b3sP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.07A 5iy5C-1p16A:
undetectable
5iy5N-1p16A:
undetectable
5iy5P-1p16A:
undetectable
5iy5C-1p16A:
20.60
5iy5N-1p16A:
20.40
5iy5P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH612_0
(NADH DEHYDROGENASE,
PUTATIVE)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
3 / 3 ARG A  35
PRO A  41
ASN A  94
None
1.01A 5jwaA-1p16A:
undetectable
5jwaH-1p16A:
undetectable
5jwaA-1p16A:
22.08
5jwaH-1p16A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KMF_A_6U9A1301_1
(ION TRANSPORT
PROTEIN)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 6 THR A  68
GLY A  70
GLU A 126
ILE A  12
G  A1167 (-4.7A)
None
G  A1167 (-3.6A)
None
0.79A 5kmfA-1p16A:
undetectable
5kmfC-1p16A:
undetectable
5kmfA-1p16A:
21.97
5kmfC-1p16A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_1
(REGULATORY PROTEIN
TETR)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 GLY A  42
ARG A 162
ASP A 145
ASP A 236
None
0.95A 5vlmB-1p16A:
undetectable
5vlmB-1p16A:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.14A 5w97A-1p16A:
undetectable
5w97C-1p16A:
undetectable
5w97c-1p16A:
undetectable
5w97A-1p16A:
20.40
5w97C-1p16A:
20.60
5w97c-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.19A 5w97C-1p16A:
undetectable
5w97a-1p16A:
undetectable
5w97c-1p16A:
undetectable
5w97C-1p16A:
20.60
5w97a-1p16A:
20.40
5w97c-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.12A 5wauA-1p16A:
undetectable
5wauC-1p16A:
undetectable
5wauc-1p16A:
undetectable
5wauA-1p16A:
20.40
5wauC-1p16A:
20.60
5wauc-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.13A 5wauC-1p16A:
undetectable
5waua-1p16A:
undetectable
5wauc-1p16A:
undetectable
5wauC-1p16A:
20.60
5waua-1p16A:
20.40
5wauc-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.11A 5x19A-1p16A:
undetectable
5x19C-1p16A:
undetectable
5x19P-1p16A:
undetectable
5x19A-1p16A:
20.40
5x19C-1p16A:
20.60
5x19P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.06A 5x1bA-1p16A:
undetectable
5x1bC-1p16A:
undetectable
5x1bP-1p16A:
undetectable
5x1bA-1p16A:
20.40
5x1bC-1p16A:
20.60
5x1bP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.07A 5x1fA-1p16A:
undetectable
5x1fC-1p16A:
undetectable
5x1fP-1p16A:
undetectable
5x1fA-1p16A:
20.40
5x1fC-1p16A:
20.60
5x1fP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.15A 5xdqA-1p16A:
undetectable
5xdqC-1p16A:
undetectable
5xdqP-1p16A:
undetectable
5xdqA-1p16A:
20.40
5xdqC-1p16A:
20.60
5xdqP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.09A 5xdqC-1p16A:
undetectable
5xdqN-1p16A:
undetectable
5xdqP-1p16A:
undetectable
5xdqC-1p16A:
20.60
5xdqN-1p16A:
20.40
5xdqP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.07A 5xdxC-1p16A:
undetectable
5xdxN-1p16A:
undetectable
5xdxP-1p16A:
undetectable
5xdxC-1p16A:
20.60
5xdxN-1p16A:
20.40
5xdxP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.16A 5z84A-1p16A:
undetectable
5z84C-1p16A:
undetectable
5z84P-1p16A:
undetectable
5z84A-1p16A:
20.40
5z84C-1p16A:
20.60
5z84P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.09A 5z84C-1p16A:
undetectable
5z84N-1p16A:
undetectable
5z84P-1p16A:
undetectable
5z84C-1p16A:
20.60
5z84N-1p16A:
20.40
5z84P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.17A 5z85A-1p16A:
undetectable
5z85C-1p16A:
undetectable
5z85P-1p16A:
undetectable
5z85A-1p16A:
20.40
5z85C-1p16A:
20.60
5z85P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.12A 5z85C-1p16A:
undetectable
5z85N-1p16A:
undetectable
5z85P-1p16A:
undetectable
5z85C-1p16A:
20.60
5z85N-1p16A:
20.40
5z85P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.17A 5z86A-1p16A:
undetectable
5z86C-1p16A:
undetectable
5z86P-1p16A:
undetectable
5z86A-1p16A:
20.40
5z86C-1p16A:
20.60
5z86P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.13A 5z86C-1p16A:
undetectable
5z86N-1p16A:
undetectable
5z86P-1p16A:
undetectable
5z86C-1p16A:
20.60
5z86N-1p16A:
20.40
5z86P-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.19A 5zcoA-1p16A:
undetectable
5zcoC-1p16A:
undetectable
5zcoP-1p16A:
undetectable
5zcoA-1p16A:
20.40
5zcoC-1p16A:
20.60
5zcoP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.12A 5zcoC-1p16A:
undetectable
5zcoN-1p16A:
undetectable
5zcoP-1p16A:
undetectable
5zcoC-1p16A:
20.60
5zcoN-1p16A:
20.40
5zcoP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.18A 5zcpA-1p16A:
undetectable
5zcpC-1p16A:
undetectable
5zcpP-1p16A:
undetectable
5zcpA-1p16A:
20.40
5zcpC-1p16A:
20.60
5zcpP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.14A 5zcpC-1p16A:
undetectable
5zcpN-1p16A:
undetectable
5zcpP-1p16A:
undetectable
5zcpC-1p16A:
20.60
5zcpN-1p16A:
20.40
5zcpP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.16A 5zcqA-1p16A:
undetectable
5zcqC-1p16A:
undetectable
5zcqP-1p16A:
undetectable
5zcqA-1p16A:
20.40
5zcqC-1p16A:
20.60
5zcqP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 8 LEU A  77
THR A 116
TYR A 117
HIS A 180
None
1.10A 6nknC-1p16A:
undetectable
6nknN-1p16A:
undetectable
6nknP-1p16A:
undetectable
6nknC-1p16A:
20.60
6nknN-1p16A:
20.40
6nknP-1p16A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
1p16 MRNA CAPPING ENZYME
ALPHA SUBUNIT

(Candida
albicans)
4 / 7 THR A 116
TYR A 117
HIS A 180
LEU A  77
None
1.06A 6nmfA-1p16A:
undetectable
6nmfC-1p16A:
undetectable
6nmfP-1p16A:
undetectable
6nmfA-1p16A:
20.40
6nmfC-1p16A:
20.60
6nmfP-1p16A:
20.60