SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p1d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1p1d GLUTAMATE RECEPTOR
INTERACTING PROTEIN
(Rattus
norvegicus) 		5 / 12 LEU A 138
ALA A 165
LEU A 130
VAL A 204
LEU A 177
 None
 1.15A 1s9pB-1p1dA:
undetectable		 1s9pB-1p1dA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 1p1d GLUTAMATE RECEPTOR
INTERACTING PROTEIN
(Rattus
norvegicus) 		5 / 9 LEU A 109
VAL A  78
ILE A  39
LEU A  72
THR A  86
 None
 1.35A 3fl9H-1p1dA:
undetectable		 3fl9H-1p1dA:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 1p1d GLUTAMATE RECEPTOR
INTERACTING PROTEIN
(Rattus
norvegicus) 		4 / 7 PRO A  65
LEU A  98
GLY A  36
GLU A  61
 None
 0.93A 3tehB-1p1dA:
0.0		 3tehB-1p1dA:
12.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TI1_A_B49A299_1
(CYCLIN-DEPENDENT
KINASE 2)		 1p1d GLUTAMATE RECEPTOR
INTERACTING PROTEIN
(Rattus
norvegicus) 		5 / 9 ILE A 159
ALA A 165
VAL A 204
LYS A 176
LEU A 206
 None
 1.14A 3ti1A-1p1dA:
undetectable		 3ti1A-1p1dA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_2
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 1p1d GLUTAMATE RECEPTOR
INTERACTING PROTEIN
(Rattus
norvegicus) 		4 / 4 VAL A 155
LEU A 154
LEU A 185
ASP A 192
 None
 1.43A 5xv7A-1p1dA:
undetectable		 5xv7A-1p1dA:
16.49