SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p1m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  55
HIS A 200
GLU A 203
HIS A 228
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.50A 1a4lA-1p1mA:
21.5		 1a4lA-1p1mA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		6 / 12 HIS A  57
LEU A  76
HIS A 200
GLU A 203
HIS A 228
ASP A 279
 NI  A9001 (-3.3A)
None
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.68A 1a4lB-1p1mA:
21.5		 1a4lB-1p1mA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		6 / 12 HIS A  55
HIS A  57
HIS A 200
GLU A 203
HIS A 228
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.54A 1a4lC-1p1mA:
21.4		 1a4lC-1p1mA:
25.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_A_BEZA295_0
(CHLOROPEROXIDASE T)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 10 GLY A 161
PHE A 162
LEU A 155
TRP A 159
LEU A 134
 None
 1.38A 1a8uA-1p1mA:
undetectable		 1a8uA-1p1mA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A8U_B_BEZB294_0
(CHLOROPEROXIDASE T)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 10 GLY A 161
PHE A 162
LEU A 155
TRP A 159
LEU A 134
 None
 1.40A 1a8uB-1p1mA:
undetectable		 1a8uB-1p1mA:
24.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DB1_A_VDXA428_2
(VITAMIN D NUCLEAR
RECEPTOR)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 LEU A 138
ILE A 214
TYR A 176
VAL A 197
 None
 1.06A 1db1A-1p1mA:
0.0		 1db1A-1p1mA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 9 GLY A 280
HIS A  57
THR A 278
SER A 248
ALA A 227
 None
NI  A9001 (-3.3A)
None
None
None
 1.36A 1gtnQ-1p1mA:
undetectable
1gtnR-1p1mA:
0.0		 1gtnQ-1p1mA:
11.70
1gtnR-1p1mA:
11.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ITU_A_CILA451_1
(RENAL DIPEPTIDASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A 173
HIS A 200
HIS A  55
ASN A 250
ASP A 279
 None
NI  A9001 (-3.4A)
NI  A9001 (-3.3A)
None
NI  A9001 (-2.6A)
 1.21A 1ituA-1p1mA:
5.4		 1ituA-1p1mA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 GLY A 321
ILE A 108
LEU A 289
ASP A 339
VAL A 112
 None
 1.17A 1jg2A-1p1mA:
undetectable		 1jg2A-1p1mA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NV8_A_SAMA300_0
(HEMK PROTEIN)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 THR A 278
GLY A 107
VAL A 373
PHE A 327
ASN A  53
 None
 1.13A 1nv8A-1p1mA:
2.8		 1nv8A-1p1mA:
25.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 10 THR A 312
LEU A 308
VAL A 264
ASP A 320
VAL A 247
 None
 1.38A 1o76A-1p1mA:
undetectable		 1o76A-1p1mA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 9 THR A 312
LEU A 308
VAL A 264
ASP A 320
VAL A 247
 None
 1.38A 1t86B-1p1mA:
undetectable		 1t86B-1p1mA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 11 LEU A  81
HIS A  55
HIS A 200
ASP A 279
GLY A 280
 None
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
NI  A9001 (-2.6A)
None
 1.21A 1zz1A-1p1mA:
undetectable		 1zz1A-1p1mA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 LEU A  81
HIS A  55
HIS A 200
ASP A 279
GLY A 280
 None
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
NI  A9001 (-2.6A)
None
 1.23A 1zz1B-1p1mA:
undetectable
1zz1C-1p1mA:
undetectable		 1zz1B-1p1mA:
23.19
1zz1C-1p1mA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 LEU A 257
HIS A  55
HIS A  57
HIS A 200
 None
NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
 0.89A 2ow9A-1p1mA:
undetectable		 2ow9A-1p1mA:
17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGF_A_ADNA501_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
ASP A 113
HIS A 200
SER A 283
ASP A 279
 NI  A9001 (-3.3A)
None
NI  A9001 (-3.4A)
None
NI  A9001 (-2.6A)
 1.43A 2pgfA-1p1mA:
21.4		 2pgfA-1p1mA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		6 / 12 HIS A  55
HIS A  57
HIS A 200
GLU A 203
HIS A 228
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.46A 2pgrA-1p1mA:
21.4		 2pgrA-1p1mA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A 200
HIS A 228
GLY A 277
HIS A  55
HIS A  57
 NI  A9001 (-3.4A)
None
None
NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
 1.17A 2pgrA-1p1mA:
21.4		 2pgrA-1p1mA:
24.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 11 LEU A  62
ALA A  58
THR A  56
ARG A 148
GLU A 151
 None
None
None
MET  A5001 (-3.9A)
None
 1.24A 2v0mD-1p1mA:
0.0		 2v0mD-1p1mA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		3 / 3 LEU A 276
MET A 316
MET A 130
 None
 1.03A 2vavF-1p1mA:
1.8		 2vavF-1p1mA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA607_1
(CHITINASE A)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 8 VAL A 125
GLY A  95
THR A  96
ALA A  99
GLU A 118
 None
 1.44A 3aruA-1p1mA:
5.6		 3aruA-1p1mA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 THR A  56
ILE A 108
LEU A 289
THR A 278
 None
 0.77A 3deuB-1p1mA:
2.1		 3deuB-1p1mA:
15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 LEU A 298
ALA A 302
PRO A 305
HIS A 362
 None
 1.15A 3gv1A-1p1mA:
undetectable
3gv1B-1p1mA:
undetectable		 3gv1A-1p1mA:
14.04
3gv1B-1p1mA:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 9 LEU A 201
HIS A 228
GLU A 203
HIS A  55
ILE A 225
 None
None
None
NI  A9001 (-3.3A)
None
 1.24A 3hy7B-1p1mA:
undetectable		 3hy7B-1p1mA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 VAL A 112
ASP A 113
THR A 189
GLY A 137
LEU A 138
 None
None
None
MET  A5001 ( 3.8A)
None
 1.31A 3j6pB-1p1mA:
0.1		 3j6pB-1p1mA:
23.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 5 LEU A 257
HIS A  55
HIS A  57
HIS A 200
 None
NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
 0.95A 3kecA-1p1mA:
undetectable		 3kecA-1p1mA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 7 GLU A 118
ASP A 113
THR A  96
ALA A  58
 None
 1.12A 3mbgA-1p1mA:
0.5
3mbgB-1p1mA:
0.5		 3mbgA-1p1mA:
13.45
3mbgB-1p1mA:
13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N58_A_ADNA500_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 LEU A 201
THR A 224
LEU A 215
LEU A 219
GLY A 218
 None
 1.38A 3n58A-1p1mA:
3.8		 3n58A-1p1mA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 10 LEU A 232
ILE A 268
VAL A 264
MET A 316
ILE A 225
 None
 0.96A 3ogqA-1p1mA:
undetectable		 3ogqA-1p1mA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 GLY A 164
GLU A 163
VAL A 125
ALA A 338
PHE A  52
 None
 1.28A 3qowA-1p1mA:
undetectable		 3qowA-1p1mA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 HIS A  57
ASP A  69
ASP A 279
ASN A 285
 NI  A9001 (-3.3A)
None
NI  A9001 (-2.6A)
None
 1.05A 3vywA-1p1mA:
undetectable		 3vywA-1p1mA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 LEU A 257
HIS A  55
HIS A  57
HIS A 200
 None
NI  A9001 (-3.3A)
NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
 0.91A 4a7bA-1p1mA:
undetectable		 4a7bA-1p1mA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		6 / 12 HIS A 200
GLU A 203
GLU A 207
HIS A 228
SER A 253
ASP A 279
 NI  A9001 (-3.4A)
None
None
None
None
NI  A9001 (-2.6A)
 0.73A 4aqlA-1p1mA:
42.5		 4aqlA-1p1mA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		6 / 12 LEU A  76
HIS A 200
GLU A 203
HIS A 228
SER A 253
ASP A 279
 None
NI  A9001 (-3.4A)
None
None
None
NI  A9001 (-2.6A)
 0.62A 4aqlA-1p1mA:
42.5		 4aqlA-1p1mA:
24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 7 ILE A 332
VAL A 342
PHE A  17
ASP A  41
 None
 1.37A 4iarA-1p1mA:
undetectable		 4iarA-1p1mA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 8 THR A 312
VAL A 264
ASP A 320
VAL A 247
 None
 0.92A 4l4bA-1p1mA:
undetectable		 4l4bA-1p1mA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 GLY A 110
LEU A 289
THR A 371
MET A 103
VAL A 368
 None
 1.44A 4okxA-1p1mA:
undetectable		 4okxA-1p1mA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
HIS A 228
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.59A 4r88A-1p1mA:
35.1		 4r88A-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_A_1LDA501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 ILE A 199
HIS A 200
HIS A  55
ASP A 279
SER A 253
 None
NI  A9001 (-3.4A)
NI  A9001 (-3.3A)
NI  A9001 (-2.6A)
None
 1.49A 4r88A-1p1mA:
35.1		 4r88A-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
GLU A 203
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.60A 4r88B-1p1mA:
35.7		 4r88B-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
GLU A 203
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.61A 4r88C-1p1mA:
35.1		 4r88C-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
GLU A 203
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.60A 4r88D-1p1mA:
35.0		 4r88D-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
GLU A 203
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.62A 4r88E-1p1mA:
34.9		 4r88E-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
HIS A 200
GLU A 203
LEU A 257
ASP A 279
 NI  A9001 (-3.3A)
NI  A9001 (-3.4A)
None
None
NI  A9001 (-2.6A)
 0.61A 4r88F-1p1mA:
35.2		 4r88F-1p1mA:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 PHE A 291
SER A 297
ALA A 296
HIS A 362
 None
 1.31A 5dzkg-1p1mA:
3.6
5dzku-1p1mA:
undetectable		 5dzkg-1p1mA:
18.38
5dzku-1p1mA:
3.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 LEU A  51
ILE A 108
GLY A 110
THR A 275
LEU A 276
 None
 0.69A 5twjA-1p1mA:
undetectable		 5twjA-1p1mA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 11 LEU A  51
ILE A 108
GLY A 110
THR A 275
LEU A 276
 None
 0.70A 5twjD-1p1mA:
undetectable		 5twjD-1p1mA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_1
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		3 / 3 GLU A 203
TRP A  75
HIS A 173
 None
 1.06A 5xipA-1p1mA:
undetectable		 5xipA-1p1mA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 LEU A 193
ALA A 190
PRO A 172
GLY A 137
LEU A 138
 None
None
None
MET  A5001 ( 3.8A)
None
 1.04A 6b0iB-1p1mA:
undetectable		 6b0iB-1p1mA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 PHE A 116
VAL A  80
LEU A 403
LEU A  87
 None
 0.95A 6e43A-1p1mA:
0.0		 6e43A-1p1mA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		4 / 6 PHE A 116
VAL A  80
LEU A 403
LEU A  87
 None
 0.96A 6e43C-1p1mA:
0.0		 6e43C-1p1mA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
LEU A  76
HIS A 200
GLU A 203
ASP A 279
 NI  A9001 (-3.3A)
None
NI  A9001 (-3.4A)
None
NI  A9001 (-2.6A)
 0.80A 6n91A-1p1mA:
22.1		 6n91A-1p1mA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)		 1p1m HYPOTHETICAL PROTEIN
TM0936
(Thermotoga
maritima) 		5 / 12 HIS A  57
LEU A  76
HIS A 200
GLU A 203
ASP A 279
 NI  A9001 (-3.3A)
None
NI  A9001 (-3.4A)
None
NI  A9001 (-2.6A)
 0.87A 6n91B-1p1mA:
22.0		 6n91B-1p1mA:
11.08