SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p27'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMA_B_NCAB700_0
(EXOTOXIN A)		 1p27 RNA-BINDING PROTEIN
8A
(Homo
sapiens) 		4 / 6 GLY B 115
TYR B 112
ALA B  84
GLU B  83
 None
 1.03A 1dmaB-1p27B:
undetectable		 1dmaB-1p27B:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
(Homo
sapiens) 		4 / 6 ARG A   8
ASP A  74
ASP A 115
GLU A  89
 None
 1.33A 1rjdA-1p27A:
undetectable		 1rjdA-1p27A:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_2
(POL POLYPROTEIN)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A
(Homo
sapiens) 		3 / 3 ASP B 107
ILE A  64
VAL A 133
 None
 0.71A 2avvD-1p27B:
undetectable		 2avvD-1p27B:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DR6_A_DM2A2002_1
(ACRB)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A
(Homo
sapiens) 		5 / 9 SER B  69
SER A 135
PHE A  26
GLY A  30
PHE B  76
 None
 1.27A 2dr6A-1p27B:
3.4		 2dr6A-1p27B:
7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
(Homo
sapiens) 		3 / 3 ARG A  27
ASP A   4
ASP A  29
 None
 0.83A 3jayA-1p27A:
undetectable		 3jayA-1p27A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
(Homo
sapiens) 		3 / 3 ARG A  27
ASP A   4
ASP A  29
 None
 0.69A 3jb3A-1p27A:
undetectable		 3jb3A-1p27A:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KK6_A_CELA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A
(Homo
sapiens) 		4 / 6 HIS B 103
VAL A  56
LEU A  22
ILE A 143
 None
 0.89A 3kk6A-1p27B:
undetectable		 3kk6A-1p27B:
12.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_1
(UNCHARACTERIZED
PROTEIN)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
RNA-BINDING PROTEIN
8A
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ARG B 109
GLU A 117
TYR A 124
 None
 0.81A 4r29D-1p27B:
undetectable		 4r29D-1p27B:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUD_D_ERMD1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2B,SOLUBLE
CYTOCHROME B562
CHIMERA)		 1p27 MAGO NASHI PROTEIN
HOMOLOG
(Homo
sapiens) 		4 / 6 LEU A 129
VAL A 133
LEU A   7
GLU A  58
 None
 0.73A 5tudD-1p27A:
undetectable		 5tudD-1p27A:
13.79