SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p2z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FML_A_RTLA401_0
(RETINOL DEHYDRATASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 12 TYR A 716
TYR A 722
TYR A 932
LEU A 668
LEU A 729
 CIT  A 969 (-4.1A)
None
None
None
None
 1.36A 1fmlA-1p2zA:
undetectable		 1fmlA-1p2zA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifA-1p2zA:
undetectable		 1kifA-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifB-1p2zA:
undetectable		 1kifB-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifC-1p2zA:
undetectable		 1kifC-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifD-1p2zA:
undetectable		 1kifD-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifE-1p2zA:
undetectable		 1kifE-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifF-1p2zA:
undetectable		 1kifF-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifG-1p2zA:
undetectable		 1kifG-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 TYR A 298
ILE A 192
ARG A 232
GLY A 231
 None
 1.22A 1kifH-1p2zA:
undetectable		 1kifH-1p2zA:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE507_0
(NAD-DEPENDENT
DEACETYLASE 2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 7 LEU A 383
ASN A 343
ILE A 345
ASP A 342
 None
 0.95A 1yc2E-1p2zA:
undetectable		 1yc2E-1p2zA:
12.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_C_H4BC1290_1
(PTERIDINE REDUCTASE
1)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 8 ARG A 691
SER A 896
LEU A 383
LEU A 662
 None
 0.92A 2bfpC-1p2zA:
undetectable		 2bfpC-1p2zA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_D_H4BD1290_1
(PTERIDINE REDUCTASE
1)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 8 ARG A 691
SER A 896
LEU A 383
LEU A 662
 None
 0.94A 2bfpD-1p2zA:
0.0		 2bfpD-1p2zA:
14.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_B_NCAB1502_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 7 ASP A 342
ARG A 391
ASP A 724
ARG A 883
 None
 1.20A 2e5dA-1p2zA:
undetectable
2e5dB-1p2zA:
undetectable		 2e5dA-1p2zA:
20.12
2e5dB-1p2zA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1290_1
(FICOLIN-2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 8 LEU A 608
SER A 622
LEU A 106
ASP A 107
 None
 1.04A 2j2pA-1p2zA:
0.0
2j2pB-1p2zA:
0.1		 2j2pA-1p2zA:
15.34
2j2pB-1p2zA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_B_CHDB1104_0
(FERROCHELATASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 LEU A 496
PRO A 497
LEU A 500
 None
 0.49A 2qd5B-1p2zA:
undetectable		 2qd5B-1p2zA:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 12 TYR A 594
LEU A 589
ILE A 584
LEU A 587
THR A 953
 None
 1.28A 2qo6A-1p2zA:
undetectable		 2qo6A-1p2zA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 10 GLY A 725
ASP A 724
THR A 703
LEU A 698
THR A 696
 None
 1.32A 3bexA-1p2zA:
undetectable
3bexB-1p2zA:
undetectable		 3bexA-1p2zA:
14.15
3bexB-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 GLY A 725
ASP A 724
THR A 703
LEU A 698
THR A 696
 None
 1.33A 3bexC-1p2zA:
undetectable
3bexD-1p2zA:
undetectable		 3bexC-1p2zA:
14.15
3bexD-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 THR A 703
LEU A 698
THR A 696
GLY A 725
ASP A 724
 None
 1.33A 3bexE-1p2zA:
undetectable
3bexF-1p2zA:
undetectable		 3bexE-1p2zA:
14.15
3bexF-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_A_PAUA248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 GLY A 725
ASP A 724
THR A 703
LEU A 698
THR A 696
 None
 1.31A 3bf1A-1p2zA:
undetectable
3bf1B-1p2zA:
undetectable		 3bf1A-1p2zA:
14.15
3bf1B-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 GLY A 725
ASP A 724
THR A 703
LEU A 698
THR A 696
 None
 1.35A 3bf1C-1p2zA:
undetectable
3bf1D-1p2zA:
undetectable		 3bf1C-1p2zA:
14.15
3bf1D-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 THR A 703
LEU A 698
THR A 696
GLY A 725
ASP A 724
 None
 1.31A 3bf1C-1p2zA:
undetectable
3bf1D-1p2zA:
undetectable		 3bf1C-1p2zA:
14.15
3bf1D-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 GLY A 725
ASP A 724
THR A 703
LEU A 698
THR A 696
 None
 1.32A 3bf1E-1p2zA:
undetectable
3bf1F-1p2zA:
undetectable		 3bf1E-1p2zA:
14.15
3bf1F-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 11 THR A 703
LEU A 698
THR A 696
GLY A 725
ASP A 724
 None
 1.33A 3bf1E-1p2zA:
undetectable
3bf1F-1p2zA:
undetectable		 3bf1E-1p2zA:
14.15
3bf1F-1p2zA:
14.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 PHE A 809
CYH A 881
PHE A 879
 None
 1.09A 3cr5X-1p2zA:
undetectable		 3cr5X-1p2zA:
6.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 8 LEU A 347
ARG A 561
ILE A 575
PHE A 340
 None
 0.90A 3ln1A-1p2zA:
undetectable		 3ln1A-1p2zA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 7 LEU A 347
ARG A 561
ILE A 575
PHE A 340
 None
 0.90A 3ln1B-1p2zA:
undetectable		 3ln1B-1p2zA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8X_A_NIMA701_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 VAL A 871
SER A 873
LEU A 865
 None
 0.71A 3n8xA-1p2zA:
undetectable		 3n8xA-1p2zA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 LEU A 383
MET A 806
ASP A 882
 None
 0.86A 3v5wA-1p2zA:
undetectable		 3v5wA-1p2zA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 8 PHE A 727
ALA A 694
LEU A 662
LEU A 383
 None
 0.88A 4ejgB-1p2zA:
undetectable		 4ejgB-1p2zA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 TYR A 807
PHE A 550
ARG A 883
 None
 1.03A 4g19D-1p2zA:
0.0		 4g19D-1p2zA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 12 VAL A 577
ALA A  81
PHE A 625
LEU A 565
PHE A 573
 None
 1.45A 4iarA-1p2zA:
undetectable		 4iarA-1p2zA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 12 THR A 644
THR A 641
ALA A 642
ALA A 638
ASN A  90
 None
 1.45A 4u15B-1p2zA:
undetectable		 4u15B-1p2zA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_2
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 5 PHE A 960
HIS A 914
LEU A 916
PRO A 959
 None
 1.23A 5csyB-1p2zA:
undetectable		 5csyB-1p2zA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_B_RCXB601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		4 / 4 LEU A 347
ARG A 561
ILE A 575
PHE A 340
 None
 0.91A 5kirB-1p2zA:
0.0		 5kirB-1p2zA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 9 ALA A 583
ILE A 584
TYR A 955
ILE A 951
LEU A 359
 None
 1.10A 5mvmA-1p2zA:
undetectable
5mvmE-1p2zA:
undetectable		 5mvmA-1p2zA:
7.22
5mvmE-1p2zA:
7.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_E_DVAE7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 TYR A  99
SER A  97
TRP A 398
 None
 1.05A 5n8jB-1p2zA:
undetectable		 5n8jB-1p2zA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_O_DVAO7_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 TYR A  99
SER A  97
TRP A 398
 None
 1.03A 5n8jA-1p2zA:
undetectable		 5n8jA-1p2zA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N8J_P_DVAP5_0
(GLY-DTY-GLY-DLE-DAL-
DSG-DVA-DAS-DGL-DSN-
DSN-GLY
STREPTAVIDIN)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 TYR A  99
SER A  97
TRP A 398
 None
 1.03A 5n8jD-1p2zA:
undetectable		 5n8jD-1p2zA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_2
(TUBULIN BETA-2B
CHAIN)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 THR A 392
PRO A 407
ARG A 410
 None
 0.85A 5nd7B-1p2zA:
undetectable		 5nd7B-1p2zA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		5 / 12 LEU A 931
PHE A 695
VAL A 933
ALA A 665
TRP A 687
 None
 1.01A 5tzoB-1p2zA:
undetectable		 5tzoB-1p2zA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 HIS A 552
SER A 611
ARG A 559
 None
 0.99A 5u63A-1p2zA:
undetectable		 5u63A-1p2zA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BER_A_DVAA2_0
(E(DVA)DP(DGL)(DHI)(D
PR)N(DAL)(DPR))		 1p2z HEXON PROTEIN
(Human
mastadenovirus
C) 		3 / 3 GLU A 921
ASP A 923
PRO A 924
 None
 0.78A 6berA-1p2zA:
undetectable		 6berA-1p2zA:
1.98