SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p32'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 7 TYR A 236
MET A 240
ASP A 241
ASP A 237
 None
 1.21A 1t03A-1p32A:
undetectable		 1t03A-1p32A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 7 LEU A  86
PHE A  82
LEU A 275
PHE A 271
 None
 1.02A 3asnP-1p32A:
undetectable
3asnW-1p32A:
undetectable		 3asnP-1p32A:
20.22
3asnW-1p32A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 7 LEU A  86
PHE A  82
LEU A 275
PHE A 271
 None
 1.04A 3asoP-1p32A:
3.0
3asoW-1p32A:
undetectable		 3asoP-1p32A:
20.22
3asoW-1p32A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 7 LYS A 119
THR A 130
VAL A 169
VAL A 183
 None
 0.55A 3em0B-1p32A:
2.6		 3em0B-1p32A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 6 LEU A  86
PHE A  82
LEU A 275
PHE A 271
 None
 1.02A 3wg7C-1p32A:
undetectable
3wg7J-1p32A:
undetectable		 3wg7C-1p32A:
20.22
3wg7J-1p32A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 6 VAL A 209
LEU A 182
CYH A 186
LEU A 243
 None
 1.25A 5hrqB-1p32A:
undetectable
5hrqI-1p32A:
undetectable
5hrqJ-1p32A:
undetectable		 5hrqB-1p32A:
14.29
5hrqI-1p32A:
6.83
5hrqJ-1p32A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 5 LEU A  86
PHE A  82
LEU A 275
PHE A 271
 None
 1.04A 5x19C-1p32A:
undetectable
5x19J-1p32A:
undetectable		 5x19C-1p32A:
20.22
5x19J-1p32A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		4 / 7 LEU A  86
PHE A  82
LEU A 275
PHE A 271
 None
 1.02A 5x1fP-1p32A:
undetectable
5x1fW-1p32A:
undetectable		 5x1fP-1p32A:
20.22
5x1fW-1p32A:
14.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_A_TLFA300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		5 / 12 VAL A 183
PHE A 204
TRP A 109
VAL A 169
PHE A 168
 None
 1.01A 6ap6A-1p32A:
undetectable		 6ap6A-1p32A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AP6_B_TLFB300_0
(PROBABLE
STRIGOLACTONE
ESTERASE DAD2)		 1p32 MITOCHONDRIAL MATRIX
PROTEIN, SF2P32
(Homo
sapiens) 		5 / 12 VAL A 183
PHE A 204
TRP A 109
VAL A 169
PHE A 168
 None
 1.03A 6ap6B-1p32A:
undetectable		 6ap6B-1p32A:
18.42