SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p3c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 GLY A 131
ALA A 174
THR A  33
ILE A  22
 None
 0.82A 1c9sU-1p3cA:
undetectable
1c9sV-1p3cA:
undetectable		 1c9sU-1p3cA:
16.00
1c9sV-1p3cA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 GLY A 131
ALA A 174
THR A  33
ILE A  22
 None
 0.83A 1gtnE-1p3cA:
undetectable
1gtnF-1p3cA:
undetectable		 1gtnE-1p3cA:
16.00
1gtnF-1p3cA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 GLY A 131
ALA A 174
THR A  33
ILE A  22
 None
 0.83A 1gtnP-1p3cA:
undetectable
1gtnQ-1p3cA:
undetectable		 1gtnP-1p3cA:
16.00
1gtnQ-1p3cA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.80A 1usqA-1p3cA:
undetectable		 1usqA-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.80A 1usqF-1p3cA:
undetectable		 1usqF-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_E_CLME1141_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.83A 2jkjE-1p3cA:
undetectable		 2jkjE-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.83A 2jklA-1p3cA:
undetectable		 2jklA-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.83A 2jklC-1p3cA:
undetectable		 2jklC-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.84A 2jklD-1p3cA:
undetectable		 2jklD-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.85A 2jklE-1p3cA:
undetectable		 2jklE-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 GLY A 134
PRO A 133
THR A  33
GLY A 169
 None
 0.85A 2jklF-1p3cA:
undetectable		 2jklF-1p3cA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 MET A 175
LEU A  43
ASN A  45
THR A 166
THR A  33
 None
 1.25A 3dcjA-1p3cA:
undetectable
3dcjB-1p3cA:
undetectable		 3dcjA-1p3cA:
20.26
3dcjB-1p3cA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 ILE A 101
PHE A 208
PHE A  98
GLY A  34
 None
 1.06A 3em0B-1p3cA:
0.0		 3em0B-1p3cA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.74A 3keeA-1p3cA:
11.8		 3keeA-1p3cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.73A 3keeB-1p3cA:
11.9		 3keeB-1p3cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.75A 3keeC-1p3cA:
11.5		 3keeC-1p3cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.73A 3keeD-1p3cA:
11.8		 3keeD-1p3cA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 7 ILE A 116
LEU A 176
THR A  33
THR A 125
 None
 1.16A 3nxuA-1p3cA:
0.0		 3nxuA-1p3cA:
15.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 TYR A 162
HIS A 186
SER A 171
ASN A  45
TYR A  88
 None
 1.44A 3r94A-1p3cA:
undetectable		 3r94A-1p3cA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.74A 3sueA-1p3cA:
10.6		 3sueA-1p3cA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.75A 3sueB-1p3cA:
10.9		 3sueB-1p3cA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.76A 3sueC-1p3cA:
10.3		 3sueC-1p3cA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.72A 3sueD-1p3cA:
10.8		 3sueD-1p3cA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.72A 3sufA-1p3cA:
10.1		 3sufA-1p3cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.73A 3sufB-1p3cA:
10.4		 3sufB-1p3cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 11 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.81A 3sufC-1p3cA:
10.1		 3sufC-1p3cA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 PHE A  27
GLY A  61
GLY A 169
ASN A  45
 None
 0.96A 3v3nB-1p3cA:
undetectable		 3v3nB-1p3cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 PHE A  27
GLY A  61
GLY A 169
ASN A  45
 None
 0.95A 3v3nC-1p3cA:
undetectable		 3v3nC-1p3cA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O2B_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA-2B
CHAIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		3 / 3 SER A 130
ALA A 174
VAL A 185
 None
 0.59A 4o2bC-1p3cA:
undetectable		 4o2bC-1p3cA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 8 ILE A  22
VAL A 100
LEU A  43
ILE A 209
 None
 0.88A 4r38D-1p3cA:
undetectable		 4r38D-1p3cA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		3 / 3 SER A 130
ALA A 174
VAL A 185
 None
 0.52A 4x1iA-1p3cA:
undetectable		 4x1iA-1p3cA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EYP_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		3 / 3 SER A 130
ALA A 174
VAL A 185
 None
 0.54A 5eypA-1p3cA:
undetectable		 5eypA-1p3cA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		6 / 12 ILE A  22
ARG A 114
LEU A 176
GLY A 172
HIS A  47
GLY A  34
 None
 1.50A 5l6eA-1p3cA:
undetectable		 5l6eA-1p3cA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ1_B_SAMB601_0
(NS5
METHYLTRANSFERASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		6 / 12 GLY A 184
GLY A  34
GLY A 172
THR A  33
VAL A  63
ILE A  42
 None
 1.48A 5wz1B-1p3cA:
undetectable		 5wz1B-1p3cA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		6 / 12 GLY A 184
GLY A  34
GLY A 172
THR A  33
VAL A  63
ILE A  42
 None
 1.48A 5wz2A-1p3cA:
undetectable		 5wz2A-1p3cA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		6 / 12 GLY A 184
GLY A  34
GLY A 172
THR A  33
VAL A  63
ILE A  42
 None
 1.50A 5wz2C-1p3cA:
undetectable		 5wz2C-1p3cA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 7 ASN A 196
HIS A 186
ASP A 135
GLY A 134
ASN A 170
 None
 1.36A 5x7pA-1p3cA:
undetectable		 5x7pA-1p3cA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1431_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 5 HIS A 186
ASP A 135
GLY A 134
ASN A 170
 None
 1.18A 5x7pB-1p3cA:
0.0		 5x7pB-1p3cA:
11.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_1
(TUBULIN ALPHA-1B
CHAIN
TUBULIN BETA CHAIN)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		3 / 3 SER A 130
ALA A 174
VAL A 185
 None
 0.48A 5xiwC-1p3cA:
undetectable		 5xiwC-1p3cA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		5 / 12 HIS A  47
ASP A  97
GLY A 169
SER A 171
ALA A 188
 None
 0.70A 6c2mC-1p3cA:
10.5		 6c2mC-1p3cA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 4 HIS A  47
LEU A 159
TYR A 161
GLY A 189
 None
 1.49A 6n91A-1p3cA:
undetectable		 6n91A-1p3cA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 1p3c GLUTAMYL-ENDOPEPTIDA
SE
(Bacillus
intermedius) 		4 / 4 HIS A  47
LEU A 159
TYR A 161
GLY A 189
 None
 1.46A 6n91B-1p3cA:
0.0		 6n91B-1p3cA:
15.35