SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p3r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1870_0
(FPRA)		 1p3r DISABLED HOMOLOG 2
(Mus
musculus) 		4 / 4 HIS A 116
PRO A 117
LYS A 120
ILE A 121
 None
 0.75A 1lqtA-1p3rA:
0.0		 1lqtA-1p3rA:
16.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p3r DISABLED HOMOLOG 2
(Mus
musculus) 		5 / 12 LEU A 158
ALA A  52
ILE A  93
ILE A 124
LEU A 162
 None
 1.17A 2jn3A-1p3rA:
1.4		 2jn3A-1p3rA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_1
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 1p3r DISABLED HOMOLOG 2
(Mus
musculus) 		3 / 3 LYS A  90
ARG A  84
ASP A 130
 None
 1.45A 3o7wA-1p3rA:
undetectable		 3o7wA-1p3rA:
19.87