SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p3y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_A_ACTA653_0 (ACETYL-COENZYME A SYNTHETASE)	1p3y	MRSD PROTEIN (Bacillus sp. HIL-Y85/54728)	4 / 5	VAL 1 111 THR 1 110 VAL 1 41 GLY 1 14	None	0.89A	2p2fA-1p3y1: 3.6	2p2fA-1p3y1: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2P2F_B_ACTB653_0 (ACETYL-COENZYME A SYNTHETASE)	1p3y	MRSD PROTEIN (Bacillus sp. HIL-Y85/54728)	4 / 4	VAL 1 111 THR 1 110 VAL 1 41 GLY 1 14	None	0.87A	2p2fB-1p3y1: 3.6	2p2fB-1p3y1: 15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RET_A_SALA201_1 (SALICYLATE BIOSYNTHESIS PROTEIN PCHB)	1p3y	MRSD PROTEIN (Bacillus sp. HIL-Y85/54728)	5 / 10	VAL 1 41 ALA 1 108 VAL 1 111 ILE 1 87 ILE 1 78	None	1.17A	3retA-1p3y1: undetectable 3retB-1p3y1: undetectable	3retA-1p3y1: 17.17 3retB-1p3y1: 17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4BLV_B_SAMB1281_0 (RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J)	1p3y	MRSD PROTEIN (Bacillus sp. HIL-Y85/54728)	5 / 12	HIS 1 73 TYR 1 85 GLY 1 14 HIS 1 75 GLY 1 67	None	1.07A	4blvB-1p3y1: 3.1	4blvB-1p3y1: 20.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2P2F_A_ACTA653_0","ACETYL-COENZYME A SYNTHETASE","1p3y","MRSD PROTEIN","Bacillus sp. HIL-Y85\/54728",4,"VAL 1 111;THR 1 110;VAL 1  41;GLY 1  14","None","0.89A","2p2fA-1p3y1:3.6","2p2fA-1p3y1:15.34"],["2P2F_B_ACTB653_0","ACETYL-COENZYME A SYNTHETASE","1p3y","MRSD PROTEIN","Bacillus sp. HIL-Y85\/54728",4,"VAL 1 111;THR 1 110;VAL 1  41;GLY 1  14","None","0.87A","2p2fB-1p3y1:3.6","2p2fB-1p3y1:15.34"],["3RET_A_SALA201_1","SALICYLATE BIOSYNTHESIS PROTEIN PCHB;SALICYLATE BIOSYNTHESIS PROTEIN PCHB","1p3y","MRSD PROTEIN","Bacillus sp. HIL-Y85\/54728",5,"VAL 1  41;ALA 1 108;VAL 1 111;ILE 1  87;ILE 1  78","None","1.17A","3retA-1p3y1:undetectable;3retB-1p3y1:undetectable","3retA-1p3y1:17.17;3retB-1p3y1:17.17"],["4BLV_B_SAMB1281_0","RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE J","1p3y","MRSD PROTEIN","Bacillus sp. HIL-Y85\/54728",5,"HIS 1  73;TYR 1  85;GLY 1  14;HIS 1  75;GLY 1  67","None","1.07A","4blvB-1p3y1:3.1","4blvB-1p3y1:20.27"]]