SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p49'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 8 GLN A 343
SER A 341
VAL A 378
GLY A 367
GLY A 374
 CA  A 605 (-2.9A)
None
None
None
None
 1.49A 1aq7A-1p49A:
undetectable		 1aq7A-1p49A:
15.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 LEU A 190
VAL A 193
LEU A 197
 None
 0.32A 1mz9B-1p49A:
undetectable		 1mz9B-1p49A:
5.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 ARG A 383
ALA A 332
ILE A 322
ILE A 272
 None
 0.88A 1oniD-1p49A:
0.2
1oniF-1p49A:
0.2		 1oniD-1p49A:
13.83
1oniF-1p49A:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.93A 1rxcB-1p49A:
undetectable		 1rxcB-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 1.00A 1rxcC-1p49A:
undetectable		 1rxcC-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.93A 1rxcE-1p49A:
undetectable		 1rxcE-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.91A 1rxcF-1p49A:
undetectable		 1rxcF-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.95A 1rxcI-1p49A:
undetectable		 1rxcI-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.94A 1rxcK-1p49A:
undetectable		 1rxcK-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.92A 1rxcL-1p49A:
undetectable		 1rxcL-1p49A:
17.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U18_B_HSMB402_1
(NITROPHORIN 1)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 5 ASP A 169
GLU A 174
THR A 165
LEU A 167
 None
None
ALS  A  75 ( 3.8A)
None
 1.14A 1u18B-1p49A:
undetectable		 1u18B-1p49A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.33A 1v8bA-1p49A:
undetectable		 1v8bA-1p49A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.34A 1v8bB-1p49A:
undetectable		 1v8bB-1p49A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_D_ADND3502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.34A 1v8bD-1p49A:
undetectable		 1v8bD-1p49A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 THR A 470
GLU A 511
HIS A 444
 None
 0.67A 1xwfA-1p49A:
0.7		 1xwfA-1p49A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 THR A 470
GLU A 511
HIS A 444
 None
 0.65A 1xwfB-1p49A:
0.6		 1xwfB-1p49A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 THR A 470
GLU A 511
HIS A 444
 None
 0.66A 1xwfC-1p49A:
1.1		 1xwfC-1p49A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 THR A 470
GLU A 511
HIS A 444
 None
 0.65A 1xwfD-1p49A:
1.1		 1xwfD-1p49A:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 LYS A 556
ASP A 546
ASN A 551
 PO4  A 606 (-3.4A)
None
PO4  A 606 ( 4.9A)
 0.87A 2bm9A-1p49A:
undetectable		 2bm9A-1p49A:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 SER A  95
LEU A  74
THR A  76
GLY A 109
 None
ALS  A  75 ( 4.0A)
ALS  A  75 ( 4.4A)
None
 0.96A 2ddwB-1p49A:
undetectable		 2ddwB-1p49A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 ARG A  51
ASP A  41
ASP A  36
 None
NAG  A 603 (-4.1A)
CA  A 605 (-2.5A)
 0.90A 2ejtA-1p49A:
undetectable		 2ejtA-1p49A:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A 164
GLN A 252
LEU A 260
ARG A 263
PHE A 237
 None
 1.37A 2oaxA-1p49A:
undetectable		 2oaxA-1p49A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A 164
GLN A 252
LEU A 260
ARG A 263
PHE A 237
 None
 1.32A 2oaxC-1p49A:
undetectable		 2oaxC-1p49A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A 164
GLN A 252
LEU A 260
ARG A 263
PHE A 237
 None
 1.38A 2oaxD-1p49A:
undetectable		 2oaxD-1p49A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_A_ADNA1_1
(YTAA PROTEIN)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 ILE A  29
ILE A 322
LEU A 326
ILE A 272
 None
 0.89A 2q83A-1p49A:
undetectable		 2q83A-1p49A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 6 PHE A 473
GLY A 374
GLY A 375
ASN A 370
 None
 0.95A 2qr2A-1p49A:
undetectable
2qr2B-1p49A:
undetectable		 2qr2A-1p49A:
16.88
2qr2B-1p49A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 6 ARG A 522
ASP A 504
ILE A 505
GLN A  67
 None
 1.09A 2ya7C-1p49A:
undetectable		 2ya7C-1p49A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.31A 3g1uB-1p49A:
undetectable		 3g1uB-1p49A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.27A 3g1uD-1p49A:
undetectable		 3g1uD-1p49A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 PRO A 379
SER A 341
ASN A 361
 None
 0.91A 3lslG-1p49A:
undetectable		 3lslG-1p49A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_E_ACHE323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 9 GLU A 267
ILE A 132
LEU A 152
TYR A 158
ASN A 247
 None
 1.47A 3rqwA-1p49A:
3.9
3rqwE-1p49A:
3.9		 3rqwA-1p49A:
19.01
3rqwE-1p49A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_F_ACHF323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 9 TYR A 158
ASN A 247
GLU A 267
ILE A 132
LEU A 152
 None
 1.45A 3rqwF-1p49A:
3.0
3rqwG-1p49A:
3.4		 3rqwF-1p49A:
19.01
3rqwG-1p49A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_H_ACHH323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 9 TYR A 158
ASN A 247
GLU A 267
ILE A 132
LEU A 152
 None
 1.44A 3rqwH-1p49A:
0.0
3rqwI-1p49A:
0.0		 3rqwH-1p49A:
19.01
3rqwI-1p49A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.97A 4e1vB-1p49A:
undetectable		 4e1vB-1p49A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 GLY A 344
ILE A  39
VAL A 378
PRO A 379
 None
 0.92A 4e1vE-1p49A:
undetectable		 4e1vE-1p49A:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 PRO A 379
TYR A  45
GLY A  40
 None
None
NAG  A 603 (-4.5A)
 0.67A 4g2zA-1p49A:
undetectable		 4g2zA-1p49A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L8F_D_MTXD301_1
(GAMMA-GLUTAMYL
HYDROLASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 11 GLY A 344
GLY A 375
GLY A 374
HIS A  68
GLN A  67
 None
 1.17A 4l8fD-1p49A:
undetectable		 4l8fD-1p49A:
19.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA306_1
(CHITOSANASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 SER A 285
ASP A  35
GLN A 343
 None
CA  A 605 (-3.1A)
CA  A 605 (-2.9A)
 0.93A 4oltA-1p49A:
undetectable
4oltB-1p49A:
undetectable		 4oltA-1p49A:
20.04
4oltB-1p49A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 PHE A 404
ILE A 421
ASP A 438
 None
 0.77A 5cswA-1p49A:
undetectable		 5cswA-1p49A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 ASP A 310
ASP A  35
LYS A 134
SER A 295
TYR A 257
 None
CA  A 605 (-3.1A)
ALS  A  75 ( 2.8A)
None
None
 1.31A 5hfjE-1p49A:
undetectable		 5hfjE-1p49A:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HJI_A_ADNA401_1
(TRNA
(GUANINE(37)-N1)-MET
HYLTRANSFERASE TRM5A)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 11 TYR A 160
PHE A 156
ILE A 132
VAL A 283
PRO A 151
 None
 1.27A 5hjiA-1p49A:
undetectable		 5hjiA-1p49A:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 PRO A 405
PHE A 118
SER A  78
ASN A 400
 None
None
ALS  A  75 ( 4.7A)
None
 0.72A 5l1fA-1p49A:
3.5
5l1fB-1p49A:
3.9		 5l1fA-1p49A:
20.42
5l1fB-1p49A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 8 TYR A 286
PHE A 299
ASN A  54
SER A 296
 None
 1.13A 5l1fA-1p49A:
3.5
5l1fB-1p49A:
3.9		 5l1fA-1p49A:
20.42
5l1fB-1p49A:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.38A 5m5kB-1p49A:
undetectable		 5m5kB-1p49A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.26A 5m66A-1p49A:
undetectable		 5m66A-1p49A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UTU_F_ADNF503_1
(ADENOSYLHOMOCYSTEINA
SE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 LEU A  31
THR A 406
GLY A 380
HIS A  68
PHE A  82
 None
 1.28A 5utuF-1p49A:
undetectable		 5utuF-1p49A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 4 PHE A 280
LEU A  58
LEU A 326
VAL A  32
 None
 1.16A 5xxiA-1p49A:
undetectable		 5xxiA-1p49A:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YF0_A_SAMA505_0
(CARNOSINE
N-METHYLTRANSFERASE)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 GLY A 110
GLY A 138
ASN A 552
SER A 140
THR A 113
 None
 1.26A 5yf0A-1p49A:
0.6		 5yf0A-1p49A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		3 / 3 ARG A 536
ARG A 424
ARG A  90
 None
 1.05A 6bplA-1p49A:
4.5
6bplB-1p49A:
undetectable		 6bplA-1p49A:
9.93
6bplB-1p49A:
9.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H0G_E_Y70E502_0
(PROTEIN CEREBLON
ZINC FINGER PROTEIN
692)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		5 / 12 ASN A 371
HIS A 444
GLU A 511
PHE A 473
GLY A 375
 None
 1.33A 6h0gE-1p49A:
0.0
6h0gF-1p49A:
undetectable		 6h0gE-1p49A:
9.66
6h0gF-1p49A:
4.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_E_AM2E301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 7 HIS A 288
THR A 261
HIS A 346
ASP A  35
 None
None
None
CA  A 605 (-3.1A)
 1.27A 6mn4E-1p49A:
undetectable		 6mn4E-1p49A:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1p49 STERYL-SULFATASE
(Homo
sapiens) 		4 / 6 ILE A 322
LEU A 323
TYR A 286
THR A 340
 None
 1.12A 6nmfN-1p49A:
undetectable
6nmfW-1p49A:
1.5		 6nmfN-1p49A:
23.37
6nmfW-1p49A:
5.91