SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p4p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		5 / 12 LEU A 186
ILE A 285
ILE A 190
ILE A 248
VAL A 203
 None
 1.01A 2ygoA-1p4pA:
undetectable		 2ygoA-1p4pA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_B_SAMB402_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		5 / 12 LEU A 168
PHE A 260
GLY A 264
ILE A 285
ASN A 188
 None
 1.34A 2zznB-1p4pA:
undetectable		 2zznB-1p4pA:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		5 / 7 LYS A 159
THR A 167
GLU A 169
VAL A 183
THR A 185
 None
 0.71A 3em0B-1p4pA:
undetectable		 3em0B-1p4pA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		3 / 3 GLN A 270
THR A 255
LEU A 291
 None
 0.73A 3ondA-1p4pA:
undetectable		 3ondA-1p4pA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		3 / 3 GLN A 270
THR A 255
LEU A 291
 None
 0.73A 3ondB-1p4pA:
undetectable		 3ondB-1p4pA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1Y_A_RBFA1176_1
(PUTATIVE PROTEASE I)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		4 / 8 ASN A 233
LYS A 206
ASN A 227
THR A 211
 None
 1.31A 4d1yA-1p4pA:
undetectable
4d1yB-1p4pA:
undetectable		 4d1yA-1p4pA:
25.57
4d1yB-1p4pA:
25.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_D_ADND502_2
(-)		 1p4p OUTER SURFACE
PROTEIN B
(Borreliella
burgdorferi) 		4 / 5 ILE A 248
GLN A 270
THR A 255
LEU A 291
 None
 1.14A 6f3mD-1p4pA:
undetectable		 6f3mD-1p4pA:
19.64