SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p50'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_E_ESTE600_1
(ESTROGEN RECEPTOR)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		4 / 8 ALA A  69
LEU A  81
HIS A  90
LEU A 275
 None
 0.90A 1ereE-1p50A:
undetectable		 1ereE-1p50A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_F_ESTF600_1
(ESTROGEN RECEPTOR)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		4 / 8 ALA A  69
LEU A  81
HIS A  90
LEU A 275
 None
 0.90A 1ereF-1p50A:
undetectable		 1ereF-1p50A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		3 / 3 LEU A 239
VAL A 242
LEU A 246
 None
 0.47A 1mz9B-1p50A:
undetectable		 1mz9B-1p50A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		3 / 3 ASN A 274
ARG A 330
ASP A 324
 NO3  A 401 (-3.1A)
None
ADP  A 400 (-3.7A)
 0.93A 2qe6A-1p50A:
undetectable		 2qe6A-1p50A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		3 / 3 ASN A 274
ARG A 330
ASP A 324
 NO3  A 401 (-3.1A)
None
ADP  A 400 (-3.7A)
 0.95A 2qe6B-1p50A:
undetectable		 2qe6B-1p50A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		4 / 5 ILE A  86
HIS A  90
TYR A  75
GLY A 276
 None
 1.07A 3b9mA-1p50A:
1.1		 3b9mA-1p50A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		5 / 12 LEU A 110
MET A 352
LEU A 239
ILE A 325
LEU A 306
 None
 1.20A 5ienB-1p50A:
0.0		 5ienB-1p50A:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		4 / 6 GLU A 149
PHE A 211
THR A 166
TYR A 167
 None
 1.36A 5lrbA-1p50A:
undetectable		 5lrbA-1p50A:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MXB_A_ML1A222_1
(CLASS 10 PLANT
PATHOGENESIS-RELATED
PROTEIN)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		5 / 10 VAL A 283
ILE A 285
LEU A 287
PHE A 119
GLY A 345
 ADP  A 400 (-4.3A)
None
None
None
None
 1.05A 5mxbA-1p50A:
1.4		 5mxbA-1p50A:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 1p50 ARGININE KINASE
(Limulus
polyphemus) 		3 / 3 THR A 166
HIS A 212
ASN A 213
 None
 1.00A 5n4tA-1p50A:
0.0		 5n4tA-1p50A:
19.40