SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p5v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	4 / 8	ALA B 141 THR B 139 PHE B 74 THR B 75	None	1.12A	2kotB-1p5vB: undetectable	2kotB-1p5vB: 21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YOE_C_FL7C1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	4 / 8	GLY B 49 ILE B 98 VAL B 102 SER B 118	None	0.84A	2yoeB-1p5vB: 0.0 2yoeC-1p5vB: 0.0	2yoeB-1p5vB: 18.18 2yoeC-1p5vB: 18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA150_0 (ILEAL BILE ACID-BINDING PROTEIN)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	5 / 12	PHE B 62 THR B 56 VAL B 113 VAL B 144 LEU B 21	None	1.04A	3elzA-1p5vB: undetectable	3elzA-1p5vB: 24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HKU_A_TORA300_1 (CARBONIC ANHYDRASE 2)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	5 / 12	ASN B 106 VAL B 60 PHE B 121 VAL B 146 LEU B 114	None	1.33A	3hkuA-1p5vB: undetectable	3hkuA-1p5vB: 21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UJ7_B_SAMB302_1 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	4 / 5	SER B 147 ASP B 111 ASP B 92 ILE B 98	None	1.40A	3uj7B-1p5vB: undetectable	3uj7B-1p5vB: 19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX6_A_FOLA201_1 (DIHYDROFOLATE REDUCTASE)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	4 / 4	ILE B 98 ASP B 111 ARG B 94 THR B 58	None	1.47A	4nx6A-1p5vB: undetectable	4nx6A-1p5vB: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NX7_A_FOLA202_1 (DIHYDROFOLATE REDUCTASE)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	4 / 4	ILE B 98 ASP B 111 ARG B 94 THR B 58	None	1.49A	4nx7A-1p5vB: undetectable	4nx7A-1p5vB: 20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGM_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	1p5v	F1 CAPSULE ANTIGEN (Yersinia pestis)	3 / 3	VAL B 146 VAL B 60 GLN B 119	None	0.67A	5qgmA-1p5vB: undetectable	5qgmA-1p5vB: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",4,"ALA B 141;THR B 139;PHE B  74;THR B  75","None","1.12A","2kotB-1p5vB:undetectable","2kotB-1p5vB:21.77"],["2YOE_C_FL7C1318_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",4,"GLY B  49;ILE B  98;VAL B 102;SER B 118","None","0.84A","2yoeB-1p5vB:0.0;2yoeC-1p5vB:0.0","2yoeB-1p5vB:18.18;2yoeC-1p5vB:18.18"],["3ELZ_A_CHDA150_0","ILEAL BILE ACID-BINDING PROTEIN","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",5,"PHE B  62;THR B  56;VAL B 113;VAL B 144;LEU B  21","None","1.04A","3elzA-1p5vB:undetectable","3elzA-1p5vB:24.18"],["3HKU_A_TORA300_1","CARBONIC ANHYDRASE 2","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",5,"ASN B 106;VAL B  60;PHE B 121;VAL B 146;LEU B 114","None","1.33A","3hkuA-1p5vB:undetectable","3hkuA-1p5vB:21.01"],["3UJ7_B_SAMB302_1","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",4,"SER B 147;ASP B 111;ASP B  92;ILE B  98","None","1.40A","3uj7B-1p5vB:undetectable","3uj7B-1p5vB:19.63"],["4NX6_A_FOLA201_1","DIHYDROFOLATE REDUCTASE","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",4,"ILE B  98;ASP B 111;ARG B  94;THR B  58","None","1.47A","4nx6A-1p5vB:undetectable","4nx6A-1p5vB:20.71"],["4NX7_A_FOLA202_1","DIHYDROFOLATE REDUCTASE","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",4,"ILE B  98;ASP B 111;ARG B  94;THR B  58","None","1.49A","4nx7A-1p5vB:undetectable","4nx7A-1p5vB:20.71"],["5QGM_A_ACTA301_0","PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7","1p5v","F1 CAPSULE ANTIGEN","Yersinia pestis",3,"VAL B 146;VAL B  60;GLN B 119","None","0.67A","5qgmA-1p5vB:undetectable","5qgmA-1p5vB:21.43"]]