SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p6f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZM_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		5 / 12 LEU A 105
GLY A 171
PRO A 103
VAL A  95
PHE A  16
 None
 1.20A 2zzmA-1p6fA:
0.0		 2zzmA-1p6fA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZN_A_SAMA401_0
(UNCHARACTERIZED
PROTEIN MJ0883)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		5 / 12 LEU A 105
GLY A 171
PRO A 103
VAL A  95
PHE A  16
 None
 1.17A 2zznA-1p6fA:
undetectable		 2zznA-1p6fA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DV1_A_SRYA1601_1
(16S RRNA
RIBOSOMAL PROTEIN
S12)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		3 / 3 LYS A  20
LYS A  22
PRO A  19
 None
 1.29A 4dv1L-1p6fA:
undetectable		 4dv1L-1p6fA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		3 / 3 VAL A 185
HIS A 108
VAL A 119
 None
 0.72A 5jmnC-1p6fA:
0.0		 5jmnC-1p6fA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJB_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		5 / 12 SER A  89
PHE A   9
TYR A  75
ILE A  26
LEU A  45
 None
 1.30A 5ljbA-1p6fA:
undetectable		 5ljbA-1p6fA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 1p6f NATURAL CYTOTOXICITY
TRIGGERING RECEPTOR
1
(Homo
sapiens) 		5 / 12 SER A  89
PHE A   9
TYR A  75
ILE A  26
LEU A  45
 None
 1.29A 5ljcA-1p6fA:
undetectable		 5ljcA-1p6fA:
16.25