SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p6p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SS4_A_ACTA411_0
(GLYOXALASE FAMILY
PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		4 / 5 VAL A  80
THR A  81
GLN A  83
ILE A  99
 None
 1.31A 1ss4A-1p6pA:
0.6		 1ss4A-1p6pA:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		7 / 12 LEU A  18
ALA A  31
THR A  53
HIS A  98
ILE A 111
LEU A 118
ARG A 120
 None
 0.80A 1tw4A-1p6pA:
19.9		 1tw4A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 11 ASN A  60
ILE A  70
VAL A  82
HIS A  98
GLN A 100
 None
 0.97A 1tw4A-1p6pA:
19.9		 1tw4A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		7 / 12 TYR A  14
LEU A  18
THR A  53
HIS A  98
ILE A 111
LEU A 118
ARG A 120
 None
 0.84A 1tw4B-1p6pA:
19.3		 1tw4B-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1TW4_B_CHDB1131_0
(FATTY ACID-BINDING
PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 10 ASN A  60
ILE A  70
VAL A  82
HIS A  98
GLN A 100
 None
 1.03A 1tw4B-1p6pA:
19.3		 1tw4B-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		6 / 12 PHE A  17
VAL A  21
ASN A  60
PHE A  62
ILE A  70
HIS A  98
 None
 0.96A 2ft9A-1p6pA:
20.6		 2ft9A-1p6pA:
73.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 11 LEU A  23
THR A  53
PRO A  54
GLN A  56
LEU A 118
 None
 1.12A 2ft9A-1p6pA:
20.6		 2ft9A-1p6pA:
73.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FT9_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		7 / 11 TYR A  14
LEU A  18
LEU A  23
THR A  53
PRO A  54
GLN A  56
ARG A 120
 None
 0.79A 2ft9A-1p6pA:
20.6		 2ft9A-1p6pA:
73.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		6 / 12 TYR A  14
ALA A  31
THR A  53
HIS A  98
ILE A 111
LEU A 118
 None
 0.87A 2jn3A-1p6pA:
18.3		 2jn3A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		6 / 12 TYR A  14
LEU A  18
ALA A  31
THR A  53
ILE A 111
LEU A 118
 None
 0.99A 2jn3A-1p6pA:
18.3		 2jn3A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		6 / 12 TYR A  14
LEU A  18
THR A  53
GLN A  56
ILE A 111
LEU A 118
 None
 0.97A 2jn3A-1p6pA:
18.3		 2jn3A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		6 / 12 TYR A  14
THR A  53
GLN A  56
HIS A  98
ILE A 111
LEU A 118
 None
 0.89A 2jn3A-1p6pA:
18.3		 2jn3A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2JN3_A_JN3A131_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 12 VAL A  49
PHE A  62
ILE A  70
LEU A  89
HIS A  98
 None
 1.00A 2jn3A-1p6pA:
18.3		 2jn3A-1p6pA:
66.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 12 TYR A  14
LEU A  18
ALA A  31
HIS A  98
ARG A 120
 None
 1.02A 2qo4A-1p6pA:
16.7		 2qo4A-1p6pA:
64.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 12 TYR A  14
LEU A  18
ALA A  31
HIS A  98
ARG A 120
 None
 1.01A 2qo6A-1p6pA:
16.7		 2qo6A-1p6pA:
64.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		5 / 12 TYR A  14
LEU A  18
LEU A  23
ALA A  31
ARG A 120
 None
 1.10A 2qo6A-1p6pA:
16.7		 2qo6A-1p6pA:
64.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		3 / 3 GLU A  41
GLY A   4
THR A   5
 None
 0.51A 3iazA-1p6pA:
undetectable		 3iazA-1p6pA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OWX_A_XRAA233_2
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		4 / 5 VAL A  37
ILE A  40
PHE A  47
PHE A  62
 None
 1.04A 3owxB-1p6pA:
undetectable		 3owxB-1p6pA:
19.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 1p6p FATTY ACID-BINDING
PROTEIN, LIVER
(Rhinella
arenarum) 		3 / 3 HIS A  98
ARG A 120
ILE A 111
 None
 0.75A 6fgdA-1p6pA:
undetectable		 6fgdA-1p6pA:
16.42