SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p6s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 1p6s RAC-BETA
SERINE/THREONINE
PROTEIN KINASE
(Homo
sapiens) 		3 / 3 ASN A  53
LEU A  78
PHE A  88
 None
 0.37A 4dajB-1p6sA:
undetectable		 4dajB-1p6sA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 1p6s RAC-BETA
SERINE/THREONINE
PROTEIN KINASE
(Homo
sapiens) 		3 / 3 ASN A  53
LEU A  78
PHE A  88
 None
 0.74A 5dsgA-1p6sA:
undetectable		 5dsgA-1p6sA:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 1p6s RAC-BETA
SERINE/THREONINE
PROTEIN KINASE
(Homo
sapiens) 		3 / 3 ASN A  54
ASP A  32
GLY A  33
 None
 0.66A 5fctB-1p6sA:
undetectable		 5fctB-1p6sA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1p6s RAC-BETA
SERINE/THREONINE
PROTEIN KINASE
(Homo
sapiens) 		4 / 4 LEU A 110
GLY A  33
SER A  34
SER A  56
 None
 1.35A 5uunA-1p6sA:
0.0		 5uunA-1p6sA:
17.42