SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1p7d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX7_B_DM2B1104_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		4 / 8 GLU A 319
GLN A 328
ILE A 240
VAL A 238
 None
 0.99A 4dx7B-1p7dA:
undetectable		 4dx7B-1p7dA:
13.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		5 / 12 LEU A 266
CYH A 217
ALA A 206
PHE A 307
THR A 284
 None
 1.44A 4iaqA-1p7dA:
undetectable		 4iaqA-1p7dA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_ACTA202_0
(RETINOL-BINDING
PROTEIN 2)		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		4 / 6 TYR A 189
GLU A 257
THR A 258
LEU A 201
 None
 1.34A 4qztA-1p7dA:
undetectable		 4qztA-1p7dA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AF6_A_GLYA507_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		3 / 3 TYR A 318
HIS A 247
MET A 255
 None
 1.14A 6af6A-1p7dA:
0.0		 6af6A-1p7dA:
25.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		3 / 3 ARG A 291
LYS A 294
ARG A 348
 None
 1.22A 6c06D-1p7dA:
undetectable		 6c06D-1p7dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DEB_B_MTXB303_1
(BIFUNCTIONAL PROTEIN
FOLD)		 1p7d INTEGRASE
(Escherichia
virus
Lambda) 		4 / 5 TYR A 318
GLN A 321
GLY A 227
ILE A 242
 None
 1.37A 6debB-1p7dA:
undetectable		 6debB-1p7dA:
15.90